Structure of African swine fever virus and associated molecular mechanisms underlying infection and immunosuppression: a review

Y Wang, W Kang, W Yang, J Zhang, D Li… - Frontiers in …, 2021 - frontiersin.org
African swine fever (ASF) is an acute, highly contagious, and deadly infectious disease. The
mortality rate of the most acute and acute ASF infection is almost 100%. The World …

African swine fever virus: a review

Z Li, W Chen, Z Qiu, Y Li, J Fan, K Wu, X Li, M Zhao… - Life, 2022 - mdpi.com
African swine fever (ASF) is a viral disease with a high fatality rate in both domestic pigs and
wild boars. ASF has greatly challenged pig-raising countries and also negatively impacted …

Transcriptome profiling in swine macrophages infected with African swine fever virus at single-cell resolution

Y Zheng, S Li, SH Li, S Yu, Q Wang… - Proceedings of the …, 2022 - National Acad Sciences
African swine fever virus (ASFV) is the causative agent of African swine fever, a highly
contagious and usually fatal disease in pigs. The pathogenesis of ASFV infection has not …

African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity

Y Ran, D Li, MG Xiong, HN Liu, T Feng, ZW Shi… - PLoS …, 2022 - journals.plos.org
ASFV is a large DNA virus that is highly pathogenic in domestic pigs. How this virus is
sensed by the innate immune system as well as why it is so virulent remains enigmatic. In …

African swine fever (ASF) diagnosis, an essential tool in the epidemiological investigation

C Gallardo, J Fernández-Pinero, M Arias - Virus research, 2019 - Elsevier
Since there is no vaccine available, prevention, control, and eradication of African swine
fever (ASF) is based on the implementation of appropriated surveillance and strict sanitary …

African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1-and JAK2-mediated signaling

D Li, J Zhang, W Yang, P Li, Y Ru, W Kang, LL Li… - Journal of Biological …, 2021 - ASBMB
African swine fever virus (ASFV) is a large DNA virus that is highly contagious and
pathogenic in domestic pigs with a mortality rate up to 100%. However, how ASFV …

Current status and evolving approaches to African swine fever vaccine development

T Teklue, Y Sun, M Abid, Y Luo… - … and emerging diseases, 2020 - Wiley Online Library
African swine fever (ASF) is a highly lethal haemorrhagic disease of swine caused by
African swine fever virus (ASFV), a unique and genetically complex virus. The disease …

Roles of African swine fever virus structural proteins in viral infection

N Jia, Y Ou, Z Pejsak, Y Zhang, J Zhang - Journal of veterinary …, 2017 - sciendo.com
African swine fever virus (ASFV) is a large, double-stranded DNA virus and the sole member
of the Asfarviridae family. ASFV infects domestic pigs, wild boars, warthogs, and bush pigs …

Inhibition of cGAS-STING-TBK1 signaling pathway by DP96R of ASFV China 2018/1

X Wang, J Wu, Y Wu, H Chen, S Zhang, J Li… - Biochemical and …, 2018 - Elsevier
African swine fever virus (ASFV) is a highly pathogenic large DNA virus that causes African
swine fever (ASF) in domestic pigs and European wild boars with mortality rate up to 100 …

Evolution in Europe of African swine fever genotype II viruses from highly to moderately virulent

C Gallardo, I Nurmoja, A Soler, V Delicado… - Veterinary …, 2018 - Elsevier
Since its arrival in the Caucasus and Russia in 2007, African swine fever virus (ASFV) has
spread widely and has now affected the EU countries of Estonia, Latvia, Lithuania, Poland …