The Natural Biotic Environment of Caenorhabditis elegans

H Schulenburg, MA Félix - Genetics, 2017 - academic.oup.com
Organisms evolve in response to their natural environment. Consideration of natural
ecological parameters are thus of key importance for our understanding of an organism's …

Interference in bacterial quorum sensing: a biopharmaceutical perspective

B Rémy, S Mion, L Plener, M Elias… - Frontiers in …, 2018 - frontiersin.org
Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …

Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

IY Hwang, E Koh, A Wong, JC March… - Nature …, 2017 - nature.com
Bacteria can be genetically engineered to kill specific pathogens or inhibit their virulence.
We previously developed a synthetic genetic system that allows a laboratory strain of …

Bacterial quorum sensing during infection

S Azimi, AD Klementiev, M Whiteley… - Annual review of …, 2020 - annualreviews.org
Bacteria are highly interactive and possess an extraordinary repertoire of intercellular
communication and social behaviors, including quorum sensing (QS). QS has been studied …

[HTML][HTML] Piwi/PRG-1 argonaute and TGF-β mediate transgenerational learned pathogenic avoidance

RS Moore, R Kaletsky, CT Murphy - Cell, 2019 - cell.com
The ability to inherit learned information from parents could be evolutionarily beneficial,
enabling progeny to better survive dangerous conditions. We discovered that, after C …

A neurotransmitter produced by gut bacteria modulates host sensory behaviour

MP O'Donnell, BW Fox, PH Chao, FC Schroeder… - Nature, 2020 - nature.com
Animals coexist in commensal, pathogenic or mutualistic relationships with complex
communities of diverse organisms, including microorganisms. Some bacteria produce …

Caenorhabditis elegans responses to bacteria from its natural habitats

BS Samuel, H Rowedder, C Braendle… - Proceedings of the …, 2016 - National Acad Sciences
Most Caenorhabditis elegans studies have used laboratory Escherichia coli as diet and
microbial environment. Here we characterize bacteria of C. elegans' natural habitats of …

Pseudomonas genomes: diverse and adaptable

MW Silby, C Winstanley, SAC Godfrey… - FEMS microbiology …, 2011 - academic.oup.com
Members of the genus Pseudomonas inhabit a wide variety of environments, which is
reflected in their versatile metabolic capacity and broad potential for adaptation to fluctuating …

A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions

U Seroussi, A Lugowski, L Wadi, RX Lao, AR Willis… - Elife, 2023 - elifesciences.org
Argonaute (AGO) proteins associate with small RNAs to direct their effector function on
complementary transcripts. The nematode Caenorhabditis elegans contains an expanded …

Understanding biofilm resistance to antibacterial agents

D Davies - Nature reviews Drug discovery, 2003 - nature.com
According to a public announcement by the US National Institutes of Health,“Biofilms are
medically important, accounting for over 80% of microbial infections in the body”. Yet …