Quinazoline derivatives: synthesis and bioactivities

D Wang, F Gao - Chemistry Central Journal, 2013 - Springer
Owing to the significant biological activities, quinazoline derivatives have drawn more and
more attention in the synthesis and bioactivities research. This review summarizes the …

New insights into chemistry and anti-infective potential of triazole scaffold

R Kharb, M Shahar Yar… - Current medicinal …, 2011 - ingentaconnect.com
Research and development for novel substances possessing anti-infective activity have
attracted considerable attention due to the escalating resistance towards conventional …

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv

S Ananthan, ER Faaleolea, RC Goldman, JV Hobrath… - Tuberculosis, 2009 - Elsevier
There is an urgent need for the discovery and development of new antitubercular agents that
target new biochemical pathways and treat drug resistant forms of the disease. One …

Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2, 4-dione derivatives

O Bozdağ-Dündar, Ö Özgen, A Menteşe… - Bioorganic & medicinal …, 2007 - Elsevier
In this study, a series of thiazolyl thiazolidine-2, 4-dione derivatives (Va–f and VIa–f) were
synthesized and evaluated for their antibacterial and antifungal activities against …

Antituberculosis activity of the molecular libraries screening center network library

JA Maddry, S Ananthan, RC Goldman, JV Hobrath… - Tuberculosis, 2009 - Elsevier
There is an urgent need for the discovery and development of new antitubercular agents that
target novel biochemical pathways and treat drug-resistant forms of the disease. One …

Metabolomic profiling in the characterization of degenerative bone and joint diseases

KR Swank, JE Furness, EA Baker, CK Gehrke… - Metabolites, 2020 - mdpi.com
Osteoarthritis and inflammatory arthropathies are a cause of significant morbidity globally.
New research elucidating the metabolic derangements associated with a variety of bone …

In vitro antibacterial activity of ten series of substituted quinazolines.

S Jantova, Š Stankovský, K Špirková - 2004 - cabidigitallibrary.org
The antibacterial activity of 10 series of substituted quinazolines (157 derivatives) against
bacterial strains Escherichia coli CCM 3988, Pseudomonas aeruginosa CCM 3955, Bacillus …

Synthesis, characterization and biological evaluation of some novel 2, 4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents

VR Avupati, RP Yejella, A Akula, GS Guntuku… - Bioorganic & medicinal …, 2012 - Elsevier
A series of some novel 2, 4-thiazolidinediones (TZDs)(2a–x) have been synthesized and
characterized by FTIR, 1H NMR, 13C NMR and LC mass spectral analysis. All the …

Design, synthesis and antibacterial activity of novel 1, 3-thiazolidine pyrimidine nucleoside analogues

SN Sriharsha, S Satish, S Shashikanth… - Bioorganic & medicinal …, 2006 - Elsevier
The synthesis of a new class of 1, 3-thiazolidine nucleoside analogues in which furanose
oxygen atom was replaced with nitrogen atom and 2′-carbon atom with sulfur atom is …

Microwave assisted synthesis of ring junction heterocyclic antioxidants

R Sompalle, SM Roopan - Research on Chemical Intermediates, 2016 - Springer
Abstract A series of 6, 7-dihydro-[1, 2, 4] triazolo [5, 1-b] quinazolin-8 (5 H)-ones, 4a–o were
synthesized via a one-pot, multicomponent reaction in the presence of water as a solvent …