Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …

Interleukin (IL)-10 is a pleiotropic cytokine known for its potent anti-inflammatory and
immunosuppressive effects. Originally identified as a product of T helper 2 cells, IL-10 is now …

When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …

RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …

Healthy immune responses require efficient protection without excessive inflammation.
Recent discoveries on the degree of fucosylation of a human N-linked glycan at a conserved …

Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing
respiratory tract infection in infants, the elderly and people with poor immune function, which …

Introduction Nirsevimab is an extended half-life (M252Y/S254T/T256E [YTE]-modified)
monoclonal antibody to the pre-fusion conformation of the respiratory syncytial virus (RSV) …

Respiratory syncytial virus (RSV) infections are a constant public health problem, especially
in infants and older adults. Virtually all children will have been infected with RSV by the age …

IgG antibodies are important mediators of vaccine-induced immunity through complement-
and Fc receptor-dependent effector functions. Both are influenced by the composition of the …