The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

Binge eating disorder (BED) shares many characteristics with addictive behaviors (eg,
diminished control, continued use despite negative consequences), and a body of scientific …

Why do we repeat choices that we know are bad for us? Decision making is characterized
by the parallel engagement of two distinct systems, goal-directed and habitual, thought to …

Context Research has implicated an addictive process in the development and maintenance
of obesity. Although parallels in neural functioning between obesity and substance …

Understanding the cognitive sequela of repeated cocaine use is a growing area of research
and is crucial to the development of cognitive models of addiction. We systematically …

Anorexia nervosa (AN) is a severe psychiatric disorder associated with food avoidance and
malnutrition. In this study, we wanted to test whether we would find brain reward alterations …

While hedonic and reward-related processes are central to drug use and dependence, this
article focuses on the contribution that cognitive processes may make to addiction. In …

The ability to predict relapse is a major goal of drug addiction research. Clinical and
diagnostic measures are useful in this regard, but these measures do not fully and …

The basic concepts underlying compulsive, impulsive and addictive behaviours overlap,
which may help explain why laymen use these expressions interchangeably. Although there …

Because negative symptoms, including motivational deficits, are a critical unmet need in
schizophrenia, there are many ongoing efforts to develop new pharmacological and …