Abstract Hydrazine (N 2 H 4) is a toxic compound widely used in agricultural, chemical,
pharmaceutical, and other industrial processes. It causes serious pollution to air, soil, and …

Novel halogenated phenoxychalcones 2a–f and their corresponding N-acetylpyrazolines 3a–
f were synthesised and evaluated for their anticancer activities against breast cancer cell …

N-acetyl pyrazoline derivatives A–C containing methoxy and chloro/hydroxyl substituents
were synthesized and tested for their cytotoxic activities. The precursor chalcones A–C …

Chloro chalcone derivatives 1-5 were synthesized by the conventional and sonochemical
method. A significant enhancing effect in reaction time was observed in chalcones synthesis …

The synthesis of N-phenylpyrazolines 1-5 was performed by the cyclocondensation of
phenylhydrazine and appropriate chalcones that have been synthesized from our previous …

Context: Metastatic breast cancer is still categorized as an incurable disease because all
available therapies are palliative treatments to relieve symptoms and increase life …

Background Multidrug resistance in various cancer types is a major obstacle in cancer
treatment. The concept of a single drug molecular target often causes treatment failure due …

One of the most typical cancers to affect women worldwide is breast cancer. Multiple routes
involving different proteins that control the development of cancer. HER-2 is a protein that …

This study was aimed to synthesize N-phenylpyrazoline derivative and evaluate its
antimalarial activity. The pyrazoline was synthesized from chalcone derivative through a …

The development of novel anticancer agents is essential in cancer prevention. One versatile
group of compounds, known for their significant bioactivity and several of its derivatives that …