Pyroptosis is an active and ordered form of programmed cell death. The signaling pathways
of pyroptosis are mainly divided into canonical pathways mediated by caspase-1 and …

Oral multi-kinase inhibitors have transformed the treatment landscape for various cancer
types and provided significant improvements in clinical outcomes. These agents are mainly …

T-cell acute lymphocytic leukemia (T-ALL) is the most common cancer in children, with a low
survival rate because of drug resistance and a high recurrence rate. Targeted delivery of …

Nucleic acid aptamers are single-stranded oligonucleotides that are selected through
exponential enrichment (SELEX) technology from synthetic DNA/RNA libraries. These …

Abstract Introduction: Mitotane (o, p'–DD) is the drug of choice for Adrenocortical
Carcinomas (ACC) and its measurement in plasma is essential to control drug …

Therapeutic drug monitoring is a strategy based on the determination of drugs' plasma
concentrations in biological fluids to individualize the dosage of drugs with a narrow …

La prise en charge des cancers est aujourd'hui une priorité de santé publique. Pour cela se
développent de plus en plus de nouveaux traitements dits de précision, et ce que l'on …

La monitorización de fármacos es una estrategia basada en la determinación de las
concentraciones plasmáticas de fármacos en fluidos biológicos para individualizar la …