Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Mitochondria are the energy factories of the cell and also serve as a checkpoint regulating
programmed cell death. Not surprisingly, dysfunctional mitochondria are implicated in a …

The structural complexity of many natural products sets them apart from common synthetic
drugs, allowing them to access a biological target space that lies beyond the enzyme active …

Covering: 1992 up to 2023 Since their discovery, lasso peptides went from peculiarities to
be recognized as a major family of ribosomally synthesized and post-translationally modified …

Senescent cells accumulate in several tissues during ageing and contribute to several
pathological processes such as ageing and cancer. Senescence induction is a complex …

Protozoa play host for many intracellular bacteria and are important for the adaptation of
pathogenic bacteria to eukaryotic cells. We analyzed the genome sequence of “Candidatus …

The biomarkers or receptors expressed on cancer cells and the targeting ligands with high
binding affinity for biomarkers play a key role in early detection and treatment of breast …

Natural microcin J25 (MccJ25) represent promising alternatives to traditional antibiotics for
the treatment of drug-resistant infections. However, little is known about the antibacterial …

Burkholderia species have emerged as a new source of diverse natural products. This mini-
review covers all of the natural products discovered in recent years from Burkholderia sp. by …

Pediocin-like bacteriocins are among the natural antimicrobial agents attracting attention as
scaffolds for the development of a new generation of antibiotics. Acidocin A has significant …