Stem cell transplantation holds great promise as a potential treatment for currently incurable
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …

Retinal diseases such as age-related macular degeneration (ARMD) and retinitis
pigmentosa (RP) affect millions of people. Replacing lost cells with new cells that connect …

purpose. To use progenitor cells isolated from the neural retina for transplantation studies in
mice with retinal degeneration. methods. Retinal progenitor cells from postnatal day 1 green …

Publisher Summary This chapter reviews the distribution and specialized differentiation of
macrophages in the nervous system, in the normal state and following injury. Macrophages …

Despite considerable effort and significant therapeutic advances, age-related macular
degeneration (AMD) remains the commonest cause of blindness in the developed world …

Retinal stem cells (RSCs) are multipotent central nervous system (CNS) precursors that give
rise to the retina during the course of development. RSCs are present in the embryonic …

Neuronal degenerations in the retina are leading causes of blindness. Like most other areas
of the CNS, the neurons of the mammalian retina are not replaced following degeneration …

Autologous peripheral nerve grafts were used to permit and direct the regrowth of retinal
ganglion cell axons from the eye to the ipsilateral superior colliculus of adult hamsters in …

The goal of the present study was threefold: to determine whether viable human retinal
progenitor cells (hRPCs) could be obtained from cadaveric retinal tissue, to evaluate marker …

Introduction: After decades of basic science research involving the testing of regenerative
strategies in animal models of retinal degenerative diseases, a number of clinical trials are …