As the world gets closer to eliminating malaria, the scientific community worldwide has
begun to realize the importance of malaria transmission-blocking interventions. The onus of …

The endochin-like quinolone (ELQ) compound class may yield effective, safe treatments for
a range of important human and animal afflictions. However, to access the public health …

Abstract 4 (1H)-quinolone is an attractive template for antimalarial drug discovery
campaigns. Given the current global increase in drug and insecticide resistance, the …

Substituted benzenoid rings are a prevalent motif in many industries including high tech,
agrochemicals, and pharmaceuticals. As a result, the arylation of chemical compounds is a …

Questa tesi evidenzia il potenziale di blocco della trasmissione degli attuali farmaci
antimalarici e di farmaci che si trovano in vari stadi di sviluppo clinico. Anche dopo aver …

Significance: P4Q-391 is an antimalarial compound that is active against both the blood and
liver stages of the Plasmodium parasite. The key step in the gram-scale synthesis depicted …