Human pluripotent stem cells in neurodegenerative diseases: potentials, advances and limitations

TA Kolagar, M Farzaneh, N Nikkar… - Current stem cell …, 2020 - ingentaconnect.com
Neurodegenerative diseases are progressive and uncontrolled gradual loss of motor
neurons function or death of neuron cells in the central nervous system (CNS) and the …

Modulation of human multipotent and pluripotent stem cells using surface nanotopographies and surface-immobilised bioactive signals: A review

PY Wang, H Thissen, P Kingshott - Acta biomaterialia, 2016 - Elsevier
The ability to control the interactions of stem cells with synthetic surfaces is proving to be
effective and essential for the quality of passaged stem cells and ultimately the success of …

Laser bioprinting of human induced pluripotent stem cells—the effect of printing and biomaterials on cell survival, pluripotency, and differentiation

L Koch, A Deiwick, A Franke, K Schwanke… - …, 2018 - iopscience.iop.org
Research on human induced pluripotent stem cells (hiPSCs) is one of the fastest growing
fields in biomedicine. Generated from patient's own somatic cells, hiPSCs can be …

Defined essential 8™ medium and vitronectin efficiently support scalable xeno-free expansion of human induced pluripotent stem cells in stirred microcarrier culture …

SM Badenes, TG Fernandes, CSM Cordeiro… - PLoS …, 2016 - journals.plos.org
Human induced pluripotent stem (hiPS) cell culture using Essential 8™ xeno-free medium
and the defined xeno-free matrix vitronectin was successfully implemented under adherent …

The impact of adhesion molecules on the in vitro culture and differentiation of stem cells

A Abdal Dayem, S Lee, H Y. Choi… - Biotechnology …, 2018 - Wiley Online Library
The term “cell adhesion” represents cell–cell interactions and the interaction between the
cell and the extracellular matrix (ECM). These interactions are crucial for the development of …

Directed differentiation of human iPSC into insulin producing cells is improved by induced expression of PDX1 and NKX6. 1 factors in IPC progenitors

MP Walczak, AM Drozd, E Stoczynska-Fidelus… - Journal of Translational …, 2016 - Springer
Background Induced pluripotent stem cells (iPSC) possess an enormous potential as both,
scientific and therapeutic tools. Their application in the regenerative medicine provides new …

Robust expansion of human pluripotent stem cells: integration of bioprocess design with transcriptomic and metabolomic characterization

MM Silva, AF Rodrigues, C Correia… - Stem cells …, 2015 - academic.oup.com
Human embryonic stem cells (hESCs) have an enormous potential as a source for cell
replacement therapies, tissue engineering, and in vitro toxicology applications. The lack of …

Long-term maintenance of human pluripotent stem cells on cRGDfK-presenting synthetic surfaces

JW Lambshead, L Meagher, J Goodwin, T Labonne… - Scientific Reports, 2018 - nature.com
Synthetic human pluripotent stem cell (hPSC) culture surfaces with defined physical and
chemical properties will facilitate improved research and therapeutic applications of hPSCs …

Hyaluronic Acid‐Based Hydrogels Enable Rod Photoreceptor Survival and Maturation In Vitro through Activation of the mTOR Pathway

N Mitrousis, RY Tam, AEG Baker… - Advanced Functional …, 2016 - Wiley Online Library
The culture of isolated photoreceptors in vitro has remained elusive in neuroscience. By
using defined hyaluronic acid (HA) hydrogels, photoreceptor survival and maturation in vitro …

Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs

Y Lin, H Liu, M Klein, J Ostrominski, SG Hong… - Scientific reports, 2018 - nature.com
Nonhuman primate (NHP) models are more predictive than rodent models for developing
induced pluripotent stem cell (iPSC)-based cell therapy, but robust and reproducible NHP …