Simulating cancer growth with multiscale agent-based modeling

Z Wang, JD Butner, R Kerketta, V Cristini… - Seminars in cancer …, 2015 - Elsevier
There have been many techniques developed in recent years to in silico model a variety of
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …

Integrative mathematical oncology

ARA Anderson, V Quaranta - Nature Reviews Cancer, 2008 - nature.com
Cancer research attracts broad resources and scientists from many disciplines, and has
produced some impressive advances in the treatment and understanding of this disease …

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer …

JS Vaidya, M Bulsara, M Baum, F Wenz, S Massarut… - bmj, 2020 - bmj.com
Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a
single dose during lumpectomy, can effectively replace postoperative whole breast external …

[HTML][HTML] Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from …

JS Vaidya, F Wenz, M Bulsara, JS Tobias, DJ Joseph… - The Lancet, 2014 - thelancet.com
Summary Background The TARGIT-A trial compared risk-adapted radiotherapy using single-
dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam …

Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority …

JS Vaidya, DJ Joseph, JS Tobias, M Bulsara, F Wenz… - The Lancet, 2010 - thelancet.com
Background After breast-conserving surgery, 90% of local recurrences occur within the
index quadrant despite the presence of multicentric cancers elsewhere in the breast. Thus …

Mathematical models of cancer: when to predict novel therapies, and when not to

R Brady, H Enderling - Bulletin of mathematical biology, 2019 - Springer
The number of publications on mathematical modeling of cancer is growing at an
exponential rate, according to PubMed records, provided by the US National Library of …

Nonlinear modelling of cancer: bridging the gap between cells and tumours

JS Lowengrub, HB Frieboes, F Jin, YL Chuang, X Li… - …, 2009 - iopscience.iop.org
Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

Mathematical modeling of tumor growth and treatment

H Enderling, M AJ Chaplain - Current pharmaceutical design, 2014 - ingentaconnect.com
Using mathematical models to simulate dynamic biological processes has a long history.
Over the past couple of decades or so, quantitative approaches have also made their way …

Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach

R Rockne, JK Rockhill, M Mrugala… - Physics in Medicine …, 2010 - iopscience.iop.org
Glioblastoma multiforme (GBM) is the most malignant form of primary brain tumors known as
gliomas. They proliferate and invade extensively and yield short life expectancies despite …

Early breast cancer

JR Benson, I Jatoi, M Keisch, FJ Esteva, A Makris… - The Lancet, 2009 - thelancet.com
Adoption of urbanised lifestyles together with changes in reproductive behaviour might
partly underlie the continued rise in worldwide incidence of breast cancer. Widespread …