The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

Abstract Background In the United States, Black men are at highest risk for being diagnosed
with and dying from prostate cancer. Given this disparity, we examined relevant data to …

Background Prostate cancer is the most diagnosed cancer in African American men, yet
prostate cancer screening regimens in this group are poorly guided by existing evidence …

One of the justifiable criticisms of human genetic studies is the underrepresentation of
participants from diverse populations. Lack of inclusion must be addressed at-scale to …

Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in
the majority of prostate cancer (PCa). PSMA has an enzymatic function that makes metabolic …

African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet,
genetic studies have largely been conducted outside the context of Sub-Saharan Africa …

Prostate cancer (PCa) is a significant health burden in Sub-Saharan Africa, with mortality
rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk …

Men of African descent have the highest prostate cancer incidence and mortality rates, yet
the genetic basis of prostate cancer in African men has been understudied. We used …

Molecular prognostic and diagnostic tools allow for targeted cancer surveillance,
prognostication, and treatment, and these assays have the potential to improve the lives of …

Aim To investigate the role of family history, race/ethnicity, and genetics in prostate cancer
(PCa) screening. Methods We conducted a systematic review of articles from January 2013 …