Small-diameter vascular tissue engineering

DG Seifu, A Purnama, K Mequanint… - Nature Reviews …, 2013 - nature.com
Vascular occlusion remains the leading cause of death in Western countries, despite
advances made in balloon angioplasty and conventional surgical intervention. Vascular …

Vascular access in haemodialysis: strengthening the Achilles' heel

MC Riella, P Roy-Chaudhury - Nature Reviews Nephrology, 2013 - nature.com
Despite all the progress achieved since Scribner first introduced the arteriovenous (AV)
shunt in 1960 and Cimino and Brescia introduced the native AV fistula in 1962, we have …

[HTML][HTML] First human use of an allogeneic tissue-engineered vascular graft for hemodialysis access

W Wystrychowski, TN McAllister, K Zagalski… - Journal of vascular …, 2014 - Elsevier
An arteriovenous fistula is the current gold standard for chronic hemodialysis access.
Tunneled catheters or synthetic grafts have poorer outcomes and much higher risks of …

Arteriovenous access failure: more than just intimal hyperplasia?

TC Rothuizen, CY Wong, PHA Quax… - Nephrology Dialysis …, 2013 - academic.oup.com
Haemodialysis vascular access patency is severely compromised by fistula non-maturation
and access stenosis. Intimal hyperplasia (IH) is considered the culprit lesion in failed fistulas …

Tissue-engineered vascular grafts and regeneration mechanisms

Y Wei, F Wang, Z Guo, Q Zhao - Journal of Molecular and Cellular …, 2022 - Elsevier
Cardiovascular diseases (CVDs) are life-threatening diseases with high morbidity and
mortality worldwide. Vascular bypass surgery is still the ultimate strategy for CVD treatment …

Rapid self-assembly of bioengineered cardiovascular bypass grafts from scaffold-stabilized, tubular bilevel cell sheets

D von Bornstädt, H Wang, MJ Paulsen, AB Goldstone… - Circulation, 2018 - Am Heart Assoc
Background: Cardiovascular bypass grafting is an essential treatment for complex cases of
atherosclerotic disease. Because the availability of autologous arterial and venous conduits …

A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: towards in situ tissue-engineered vascular accesses for haemodialysis

S van Uden, N Vanerio, V Catto… - Biomedical …, 2019 - iopscience.iop.org
Clinically available alternatives of vascular access for long-term haemodialysis—currently
limited to native arteriovenous fistulae and synthetic grafts—suffer from several drawbacks …

Bioengineered human arteries for the repair of vascular injuries

EE Moore, M Curi, N Namias, R Kundi, YW Lum… - JAMA …, 2024 - jamanetwork.com
Importance Vascular injuries require urgent repair to minimize loss of limb and life. Standard
revascularization relies on autologous vein or synthetic grafts, but alternative options are …

Biomaterial-associated infection: a perspective from the clinic

W Zimmerli, A Trampuz - Biomaterials associated infection: immunological …, 2012 - Springer
Implant-associated infections are caused by microorganisms which adhere to the device
and form biofilms. Medical devices are highly susceptible to bacterial and fungal infections …

A novel hybrid silk fibroin/polyurethane arteriovenous graft for hemodialysis: proof‐of‐concept animal study in an ovine model

SA Riboldi, M Tozzi, M Bagardi… - Advanced …, 2020 - Wiley Online Library
To solve the problem of vascular access failure, a novel semi‐degradable hybrid vascular
graft, manufactured by electrospinning using silk fibroin and polyurethane (Silkothane), has …