Curcumin, inflammation, and chronic diseases: how are they linked?

Y He, Y Yue, X Zheng, K Zhang, S Chen, Z Du - Molecules, 2015 - mdpi.com
It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

[HTML][HTML] Cancer prevention and therapy through the modulation of the tumor microenvironment

SC Casey, A Amedei, K Aquilano, AS Azmi… - Seminars in cancer …, 2015 - Elsevier
Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress

JH Park, BM Lee, HS Kim - Journal of Toxicology and …, 2021 - Taylor & Francis
Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against
several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties …

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation

X Zhang, X Wang, T Wu, B Li, T Liu, R Wang, Q Liu… - Scientific reports, 2015 - nature.com
Isoliensinine, liensinine and neferine are major bisbenzylisoquinoline alkaloids in the seed
embryo of lotus (Nelumbo nucifera) and exhibit potential anti-cancer activity. Here, we …

Curcumin as a potential protective compound against cardiac diseases

S Jiang, J Han, T Li, Z Xin, Z Ma, W Di, W Hu… - Pharmacological …, 2017 - Elsevier
Curcumin, which was first used 3000 years ago as an anti-inflammatory agent, is a well-
known bioactive compound derived from the active ingredient of turmeric (Curcuma longa) …

Spices and atherosclerosis

PF Tsui, CS Lin, LJ Ho, JH Lai - Nutrients, 2018 - mdpi.com
Cardiovascular disease is one of the leading causes of death and disability in the world.
Atherosclerosis, characterized by lipid accumulation and chronic inflammation in the vessel …

Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/JNK activation

L Xu, X Zhang, Y Li, S Lu, S Lu, J Li, Y Wang, X Tian… - Tumor Biology, 2016 - Springer
Ovarian cancer is the most lethal gynecological malignancy. Patients usually have poor
prognosis because of late diagnosis, relapse, and chemoresistance. It is pressing to seek …

Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells

BN Waghela, A Sharma, S Dhumale, SM Pandey… - PloS one, 2015 - journals.plos.org
Curcumin, an ingredient of turmeric, exhibits a variety of biological activities such as anti-
inflammatory, anti-atherosclerotic, anti-proliferative, anti-oxidant, anti-cancer and anti …

[HTML][HTML] Targeting cancer cell metabolism: The combination of metformin and 2-Deoxyglucose regulates apoptosis in ovarian cancer cells via p38 MAPK/JNK …

J Zhu, Y Zheng, H Zhang, H Sun - American journal of translational …, 2016 - ncbi.nlm.nih.gov
Targeting cancer cell metabolism is a new promising strategy to fight cancer. Metformin, a
first-line treatment for type 2 diabetes mellitus, exerts anti-cancer and anti-proliferative …