Both quality improvement and clinical research efforts over the past few decades have
focused on consensus definition of sepsis and acute respiratory distress syndrome (ARDS) …

Life expectancy has gradually grown over the last century. This has deeply affected
healthcare costs, since the growth of an aging population is correlated to the increasing …

Executive Summary The EC Directive 2013/59/Euratom states in article 56 that exposures of
target volumes in nuclear medicine treatments shall be individually planned and their …

Medical laboratory services enable precise measurement of thousands of biomolecules and
have become an inseparable part of high-quality healthcare services, exerting a profound …

Objective The term 'precision medicine'describes a rational treatment strategy tailored to one
person that reverses or modifies the disease pathophysiology. In epilepsy, single case and …

Since ancient times the concept of dose response, from a toxicological perspective, has
been a matter of concern. Already by the 8th century BC and over the years, many …

Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

Exposure of humans to xenobiotic mixtures is a continuous state during their everyday
routine. However, the majority of toxicological studies assess the in vivo effects of individual …

Introduction: Epigenetics is the study of reversible modifications to chromatin and their
extensive and profound effects on gene regulation. To date, the role of epigenetics in …

The first evidence of individual targeting medicine appeared in ancient times thousands of
years ago. Various therapeutic approaches have been established since then. However …