Type 2 immunity is orchestrated by a canonical group of cytokines primarily produced by
innate lymphoid cells, group 2, and their adaptive counterparts, CD4+ helper type 2 cells …

Innate lymphoid cells (ILCs) are heterogeneous innate immune cells which participate in
host defense, mucosal repair and immunopathology by producing effector cytokines …

Group 2 innate lymphoid cells (ILC2s) are a subset of innate lymphocytes that produce type
2 cytokines, including IL-4, IL-5, and IL-13. GATA3 is a critical transcription factor for ILC2 …

Severe airway inflammatory disorders impose a significant societal burden, and the
available treatments are unsatisfactory. High levels of neutrophil extracellular trap (NET) and …

The cohesin protein complex extrudes chromatin loops, stopping at CTCF-bound sites, to
organize chromosomes into topologically associated domains, yet the biological …

Although seemingly unrelated, parasitic worms, venoms, and allergens all induce a type 2
immune response. The effector functions and clinical features of type 2 immunity are well …

Type 2 innate lymphoid cells (ILC2s) have emerged as pivotal regulators in the
pathogenesis of diseases, with their roles in inflammation, metabolism, and tissue …

Immune cells responding to pathogens undergo molecular changes that are intimately
linked to genome organization. Recent work has demonstrated that natural killer (NK) and …

Innate lymphoid cells (ILCs) have emerged as critical tissue-resident lymphocytes that
coordinate responses to environmental stress and injury. Traditionally, their function was …

Innate lymphoid cells (ILCs) lack antigen‐specific receptors and are considered the innate
arm of the immune system, phenotypically and functionally mirroring CD4+ helper T cells …