Diabetes mellitus (DM) is a major world health problem and one of the most studied
diseases, which are highly prevalent in the whole world, it is frequently associated with …

Liver sinusoidal endothelial cells (LSECs) present unique, highly specialised endothelial
cells in the body. Unlike the structure and function of typical, vascular endothelial cells …

Abstract Endothelin-1 (ET-1) is elevated in patients with obesity; however, its contribution to
the pathophysiology related to obesity is not fully understood. We hypothesized that high ET …

Ethnopharmacological relevance Chemical hepatotoxicity, especially alcoholic liver injury
(ALI), commonly occurs in young and middle-aged people who drink heavily. ALI is …

Arsenic exposure is well documented to cause serious health hazards, such as
cardiovascular abnormalities, neurotoxicity and nephrotoxicity. In the present study, we …

Aim: The purpose of this study was development, validation and application of ultra-
performance liquid chromatography (UPLC)–ESI–MS/MS method for quantitation of …

Aim To investigate the relationship between the degree of liver dysfunction, quantified by
maximal liver function capacity (LiMAx test) and endothelin-1, TNF-α and IL-6 in septic …

In the present study, the hypoglycemic, hypolipidemic, and antioxidative effects of metformin
(MET) combined with Jiang Tang Xiao Ke (JTXK) granule derived from the “Di Huang Tang” …

Background and aims Hepatic vascular hyperreactivity to vasoconstrictors is a possible
underlying mechanism of the increased intrahepatic vascular resistance in early NAFLD …

Diabetes is one of the most prevalent diseases worldwide, and hundreds of millions of
patients are suffering from diabetes and its serious complications. Early detection and early …