Natriuretic Peptide Signaling in Uterine Biology and Preeclampsia

Q Wu - International Journal of Molecular Sciences, 2023 - mdpi.com
Endometrial decidualization is a uterine process essential for spiral artery remodeling,
embryo implantation, and trophoblast invasion. Defects in endometrial decidualization and …

Recent advances in understanding the mechanistic role of transient receptor potential ion channels in hypertension.

FJ Rios, RD Sarafian, LL Camargo… - Canadian Journal of …, 2023 - Elsevier
The transient receptor potential (TRP) channel superfamily is a group of non-selective cation
channels functioning as cellular sensors for a wide range of physical, chemical and …

Genetic associations of circulating cardiovascular proteins with gestational hypertension and preeclampsia

A Schuermans, B Truong, M Ardissino… - JAMA …, 2024 - jamanetwork.com
Importance Hypertensive disorders of pregnancy (HDPs), including gestational hypertension
and preeclampsia, are important contributors to maternal morbidity and mortality worldwide …

Proteome-and Transcriptome-Wide Genetic Analysis Identifies Biological Pathways and Candidate Drug Targets for Preeclampsia

M Ardissino, B Truong, EAW Slob… - Circulation: Genomic …, 2024 - ahajournals.org
BACKGROUND: Preeclampsia is a leading cause of maternal and perinatal morbidity and
mortality. However, the current understanding of its underlying biological pathways remains …

Patterns of Gestational Hypertension or Preeclampsia Across 2 Pregnancies in Relationship to Chronic Hypertension Development: A Retrospective Cohort Study

J Mussa, E Rahme, M Dahhou, M Nakhla… - Journal of the …, 2024 - ahajournals.org
Background Gestational hypertension (GHTN) and preeclampsia are established risk
indicators for chronic hypertension. While recurrence is associated with a greater risk, it is …

Placental exosomes in pregnancy and preeclampsia

K Nishi, D Modi - American Journal of Reproductive …, 2024 - Wiley Online Library
Preeclampsia, poses significant risks to both maternal and fetal well‐being. Exosomes
released by the placenta play a crucial role in intercellular communication and are …

Parental genetically predicted liability for coronary heart disease and risk of adverse pregnancy outcomes: a cohort study

Á Hernáez, KH Skåra, CM Page, VR Mitter… - BMC medicine, 2024 - Springer
Background Adverse pregnancy outcomes (APO) may unmask or exacerbate a woman's
underlying risk for coronary heart disease (CHD). We estimated associations of maternal …

Preeclampsia: A comprehensive review

M Ali, M Ahmed, M Memon, F Chandio, Q Shaikh… - Clinica Chimica …, 2024 - Elsevier
Preeclampsia (PE) is a life-threatening disease of pregnancy and a prominent cause of
neonatal and maternal mortality and morbidity. PE affects approximately 5–10% of …

10. Role of high dimensional technology in preeclampsia (omics in preeclampsia)

L Youssef, L Testa, F Crovetto, F Crispi - Best Practice & Research Clinical …, 2023 - Elsevier
Preeclampsia is a pregnancy-specific disease that has no known precise cause. Integrative
biology approach based on multi-omics has been applied to identify upstream pathways and …

[HTML][HTML] The Role of Furin and Its Therapeutic Potential in Cardiovascular Disease Risk

H Fry, M Mazidi, C Kartsonaki, R Clarke… - International Journal of …, 2024 - mdpi.com
Furin is an important proteolytic enzyme, converting several proteins from inactive
precursors to their active forms. Recently, proteo-genomic analyses in European and East …