Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

The rise of the “Top Down” method in the field of mass spectrometry-based proteomics has
ushered in a new age of promise and challenge for the characterization and identification of …

The physiological response to infections and injuries involves local inflammation and the
initiation of events leading to a systemic response, also called acute phase reaction (APR) …

Most methods for the analysis of oligosaccharides from biological sources require a glycan
derivatization step: glycans may be derivatized to introduce a chromophore or fluorophore …

Therapeutic monoclonal antibodies (mAbs) are glycoproteins produced by living cell
systems. The glycan moieties attached to the proteins can directly affect protein stability …

A multitude of monoclonal IgG antibodies directed against a variety of therapeutic targets is
currently being developed and produced by biotechnological companies. The biological …

Glycosylation defines the adhesive properties of animal cell surfaces and the surrounding
extracellular environments. Because cells respond to stimuli by altering glycan expression …

Glycomics and glycoproteomics analyses by mass spectrometry require efficient front-end
separation methods to enable deep characterization of heterogeneous glycoform …

Over the last two decades, coupled capillary electrophoresis (CE)–mass spectrometry (MS)
has developed into a generally accepted technique with a wide applicability. A growing …

Capillary electrophoresis coupled to time-of-flight mass spectrometry (CE–TOF-MS) via a
porous tip sheathless electrospray ionization (ESI) interface was studied for the …