Since the Neolithic period, humans have domesticated herbivores to have food readily at
hand. The cohabitation with animals brought various advantages that drastically changed …

Coxiella burnetii is an intracellular bacterium that causes acute and chronic Q fever. This
unique pathogen has been historically challenging to study due to obstacles in genetically …

Intracellular bacteria have developed numerous strategies to hijack host vesicular trafficking
pathways to form their unique replicative niches. To promote intracellular replication, the …

In adapting to the intracellular niche, obligate intracellular bacteria usually undergo a
reduction of genome size by eliminating genes not needed for intracellular survival. These …

Abstract STING (STimulator of Interferon Genes) is a cytosolic sensor for cyclic dinucleotides
(CDNs) and initiates an innate immune response upon binding to CDNs. Coxiella burnetii is …

Abstract The Q-GAPS (Q fever GermAn interdisciplinary Program for reSearch) consortium
was launched in 2017 as a German consortium of more than 20 scientists with exceptional …

Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human
Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in …

Interactions between eukaryotic hosts and their bacterial symbionts drive key ecological and
evolutionary processes, from regulating ecosystems to the evolution of complex molecular …

Background Coxiella burnetii is a zoonotic pathogen that resides in wild and domesticated
animals across the globe and causes a febrile illness, Q fever, in humans. An improved …

Stenotrophomonas maltophilia is an emerging opportunistic and nosocomial pathogen. S.
maltophilia is also a risk factor for lung exacerbations in cystic fibrosis patients. S …