Regeneration is one of the great mysteries of biology. Planarians are flatworms capable of
dramatic feats of regeneration, which have been studied for over 2 centuries. Recent …

Planarians are members of the Platyhelminthes (flatworms). These animals have evolved a
remarkable stem cell system. A single pluripotent adult stem cell type (“neoblast”) gives rise …

INTRODUCTION The complete sequence of animal genomes has had a transformative
impact on biological research. Whereas the genome sequence of an organism contains the …

Planarian whole-body regeneration is enabled by stem cells called neoblasts. At least some
neoblasts are individually pluripotent. Neoblasts are also heterogeneous, with …

Having an almost unlimited capacity to regenerate tissues lost to age and injury, planarians
have long fascinated naturalists. In the Western hemisphere alone, their documented history …

Regeneration is widespread throughout the animal kingdom, but our molecular
understanding of this process in adult animals remains poorly understood. Wnt/β-catenin …

Planarian flatworms are an exception among bilaterians in that they possess a large pool of
adult stem cells that enables them to promptly regenerate any part of their body, including …

Species capable of regenerating lost body parts occur throughout the animal kingdom, yet
close relatives are often regeneration incompetent,. Why in the face of 'survival of the …

Freshwater planaria possess extreme regeneration capabilities mediated by abundant,
pluripotent stem cells (neoblasts) in adult animals. Although planaria emerged as an …

Background Planarian stem cells, or neoblasts, drive the almost unlimited regeneration
capacities of freshwater planarians. Neoblasts are traditionally described by their …