Small extracellular vesicles: Yields, functionalization and applications in diabetic wound management

X Liu, Q Wei, Z Sun, S Cui, X Wan, Z Chu… - Interdisciplinary …, 2023 - Wiley Online Library
Diabetic wounds have imposed a significant burden on both patients and society with
prolonged healing processes hindered by dysfunctional skin repair cells. Small extracellular …

Evolving understanding of autoimmune mechanisms and new therapeutic strategies of autoimmune disorders

Y Song, J Li, Y Wu - Signal Transduction and Targeted Therapy, 2024 - nature.com
Autoimmune disorders are characterized by aberrant T cell and B cell reactivity to the body's
own components, resulting in tissue destruction and organ dysfunction. Autoimmune …

[HTML][HTML] Chimeric antigen receptor (CAR) T-cell therapy: harnessing extracellular vesicles for enhanced efficacy

B Spokeviciute, S Kholia, MF Brizzi - Pharmacological Research, 2024 - Elsevier
A cutting-edge approach in cell-based immunotherapy for combating resistant cancer
involves genetically engineered chimeric antigen receptor T (CAR-T) lymphocytes. In recent …

Employing the Anchor DSPE-PEG as a Redox Probe for Ratiometric Electrochemical Detection of Surface Proteins on Extracellular Vesicles with Aptamers

K Chang, Y Fang, P He, C Zhu, X Liu, D Zheng… - Analytical …, 2023 - ACS Publications
Quantitative analysis of surface proteins on extracellular vesicles (EVs) has been
considered to be a crucial approach for reflecting the status of diseases. Due to the diverse …

Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of type 1 diabetes

C Rao, DT Cater, S Roy, J Xu, AG De Oliveira… - Diabetologia, 2024 - Springer
Aims/hypothesis Surviving beta cells in type 1 diabetes respond to inflammation by
upregulating programmed death-ligand 1 (PD-L1) to engage immune cell programmed …

Recent advances in therapeutic engineered extracellular vesicles

C Yao, H Zhang, C Wang - Nanoscale, 2024 - pubs.rsc.org
Extracellular vesicles (EVs) are natural particles secreted by living cells, which hold
significant potential for various therapeutic applications. Native EVs have specific …

Optical imaging of single extracellular vesicles: Recent progress and prospects

B Ma, L Li, Y Bao, L Yuan, S Liu, L Qi… - … & Biomedical Imaging, 2023 - ACS Publications
Extracellular vesicles (EVs) are small, membrane-bound structures released by various cell
types into the extracellular environment, which play a crucial role in intercellular …

[HTML][HTML] Beta-Cell-Derived Extracellular Vesicles: Mediators of Intercellular Communication in the Islet Microenvironment in Type 1 Diabetes

MC Dekkers, X Pu, A Enciso-Martinez, A Zaldumbide - Cells, 2024 - mdpi.com
Type 1 diabetes (T1D) is a chronic autoimmune disorder characterised by an autoimmune
response specifically mounted against the insulin-producing beta cells. Within the islet, high …

Granular Hydrogels for Harnessing the Immune Response

AE Widener, A Roberts… - Advanced Healthcare …, 2024 - Wiley Online Library
This review aims to understand the current progress in immune‐instructive granular
hydrogels and identify the key features used as immunomodulatory strategies. Published …

[HTML][HTML] Identification of crucial extracellular genes as potential biomarkers in newly diagnosed Type 1 diabetes via integrated bioinformatics analysis

M Gao, Q Liu, L Zhang, F Tabak, Y Hua, W Shao, Y Li… - PeerJ, 2025 - peerj.com
Identification of crucial extracellular genes as potential biomarkers in newly diagnosed Type
1 diabetes via integrated bioinformatics analysis [PeerJ] Related research Download Share …