Osteoporosis is a global public health problem, with fractures contributing to significant morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …
JP Luyendyk, JG Schoenecker… - Blood, The Journal of the …, 2019 - ashpublications.org
The canonical role of the hemostatic and fibrinolytic systems is to maintain vascular integrity. Perturbations in either system can prompt primary pathological end points of hemorrhage or …
MA Clynes, CL Gregson, O Bruyère, C Cooper… - …, 2021 - academic.oup.com
The coexistence of osteoporosis and sarcopenia has been recently considered in some groups as a syndrome termed 'osteosarcopenia'. Osteoporosis describes low bone mass …
Background The association between obesity and fracture risk may be skeletal site-and sex- specific but results among studies are inconsistent. Whilst several studies reported higher …
H Johansson, JA Kanis, A Odén… - Journal of bone and …, 2014 - academic.oup.com
Several recent studies suggest that obesity may be a risk factor for fracture. The aim of this study was to investigate the association between body mass index (BMI) and future fracture …
W Chen, H Lv, S Liu, B Liu, Y Zhu, X Chen… - The Lancet Global …, 2017 - thelancet.com
Background Traumatic fractures place a substantial burden on health-care systems worldwide. Although detailed information about incidence, distribution, and risk factors for …
J Stewart Williams, P Kowal, H Hestekin, T O'Driscoll… - BMC medicine, 2015 - Springer
Background In 2010 falls were responsible for approximately 80% of disability stemming from unintentional injuries excluding traffic accidents in adults 50 years and over. Falls are …
Recent evidence demonstrating an increased fracture risk among obese individuals suggests that adipose tissue may negatively impact bone health, challenging the traditional …
SA Shapses, LC Pop, Y Wang - Nutrition research, 2017 - Elsevier
Accumulating evidence supports a complex relationship between adiposity and osteoporosis in overweight/obese individuals, with local interactions and endocrine …