Estrogen and progesterone receptors in breast cancer

CH Yip, A Rhodes - Future oncology, 2014 - Taylor & Francis
Breast cancer is the most common cancer in women worldwide. The majority of breast
cancers show overexpression of estrogen receptors (ERs) and progesterone receptors …

Biomarkers for the clinical management of breast cancer: international perspective

N Patani, LA Martin, M Dowsett - International journal of cancer, 2013 - Wiley Online Library
The higher incidence of breast cancer in developed countries has been tempered by
reductions in mortality, largely attributable to mammographic screening programmes and …

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

XR Yang, J Chang-Claude, EL Goode… - Journal of the …, 2011 - academic.oup.com
Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors …

Breast cancer survival defined by the ER/PR/HER2 subtypes and a surrogate classification according to tumor grade and immunohistochemical biomarkers

CA Parise, V Caggiano - Journal of cancer epidemiology, 2014 - Wiley Online Library
Introduction. ER, PR, and HER2 are routinely available in breast cancer specimens. The
purpose of this study is to contrast breast cancer‐specific survival for the eight ER/PR/HER2 …

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

SC Dixon-Suen, SJ Lewis, RM Martin… - British journal of sports …, 2022 - bjsm.bmj.com
Objectives Physical inactivity and sedentary behaviour are associated with higher breast
cancer risk in observational studies, but ascribing causality is difficult. Mendelian …

Breast cancer subtypes as defined by the estrogen receptor (ER), progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2) among …

CA Parise, KR Bauer, MM Brown… - The breast …, 2009 - Wiley Online Library
Breast cancer research examining either molecular profiles or biomarker subtypes has
focused on the estrogen receptor negative/progesterone receptor negative/human …

Clinicopathological characteristics and breast cancer–specific survival of patients with single hormone receptor–positive breast cancer

Y Li, D Yang, X Yin, X Zhang, J Huang, Y Wu… - JAMA network …, 2020 - jamanetwork.com
Importance Steroid hormone receptors, including estrogen receptor (ER) and progesterone
receptor (PR), are crucial biomarkers in breast cancer (BC). However, limited data are …

Combinatorial biomarker expression in breast cancer

EA Rakha, JS Reis-Filho, IO Ellis - Breast cancer research and treatment, 2010 - Springer
Current clinical management of breast cancer relies on the availability of robust
clinicopathological variables and few well-defined biological markers. Recent microarray …

Poor prognosis of single hormone receptor-positive breast cancer: similar outcome as triple-negative breast cancer

SY Bae, S Kim, JH Lee, H Lee, SK Lee, WH Kil… - BMC cancer, 2015 - Springer
Background Response to endocrine therapy in breast cancer correlates with estrogen
receptor (ER) and progesterone receptor (PR) status. Generally, hormone receptor-positive …

Deciphering the divergent roles of progestogens in breast cancer

JS Carroll, TE Hickey, GA Tarulli, M Williams… - Nature Reviews …, 2017 - nature.com
Most breast cancers are driven by oestrogen receptor-α. Anti-oestrogenic drugs are the
standard treatment for these breast cancers; however, treatment resistance is common …