Propofol detection for monitoring of intravenous anaesthesia: a review

DC Ferrier, J Kiely, R Luxton - Journal of Clinical Monitoring and …, 2022 - Springer
This paper presents a review of established and emerging methods for detecting and
quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of …

Clinical effects and lethal and forensic aspects of propofol

RJ Levy - Journal of Forensic Sciences, 2011 - Wiley Online Library
Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and
unconsciousness. The potential for propofol dependency, recreational use, and abuse has …

Ti3C2Tx-rGO-chitosan-based microcatheter sensor for real-time continuous monitoring of propofol: toward improved anesthetic management

C Kafley, RP K, S Kummari, K Lakavath, YG Kotagiri - Microchimica Acta, 2023 - Springer
We are aiming to develop an electrochemical microcatheter sensor for the detection and real-
time continuous monitoring of propofol (PPF), which is an anesthetic drug majorly used …

An integrated microcatheter-based dual-analyte sensor system for simultaneous, real-time measurement of propofol and fentanyl

C Moonla, KY Goud, H Teymourian, T Tangkuaram… - Talanta, 2020 - Elsevier
Abstract According to the American Society of Anesthesiologists Closed Claims Database,
one of three drug-related errors is the result administrating an incorrect dose. Directly …

Second-hand exposure to aerosolized intravenous anesthetics propofol and fentanyl may cause sensitization and subsequent opiate addiction among …

PF McAuliffe, MS Gold, L Bajpai, ML Merves… - Medical hypotheses, 2006 - Elsevier
We hypothesize that aerosolization of anesthetics administered intravenously to patients in
the operating room may be an unintended source of exposure to physicians. This may lead …

Propofol detection and quantification in human blood: the promise of feedback controlled, closed-loop anesthesia

F Kivlehan, E Chaum, E Lindner - Analyst, 2015 - pubs.rsc.org
The performance of a membrane-coated voltammetric sensor for propofol (2, 6-
diisopropylphenol) has been characterized in long term monitoring experiments using an …

Quantitative measurement of propofol and in main glucuroconjugate metabolites in human plasma using solid phase extraction–liquid chromatography–tandem mass …

S Cohen, F Lhuillier, Y Mouloua, B Vignal… - … of Chromatography B, 2007 - Elsevier
A high-performance liquid chromatographic method coupled with tandem mass
spectrometry detection has been developed for the determination of propofol and its main …

A rapid and simple HPLC method for the analysis of propofol in biological fluids

X Cussonneau, E De Smet, K Lantsoght… - … of pharmaceutical and …, 2007 - Elsevier
A selective and sensitive high-performance liquid chromatographic method for the analysis
of propofol in biological samples was developed. Propofol and thymol (internal standard) …

Comparison of GC/MS and LC/MS methods for the analysis of propofol and its metabolites in urine

SY Lee, NH Park, EK Jeong, JW Wi, CJ Kim… - … of Chromatography B, 2012 - Elsevier
Gas chromatography–mass spectrometry (GC/MS) and liquid chromatography–mass
spectrometry (LC/MS) were compared for their capacity to metabolite identification …

The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice

E Nozohouri, Y Ahn, S Zoubi, D Patel, SR Archie… - Pharmaceutical …, 2024 - Springer
Purpose We investigated whether short term infusion of propofol, a highly lipophilic agonist
at GABAA receptors, which is in widespread clinical use as anesthetic and sedative, affects …