Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …

Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for
the generation of library of enormous lead molecules. Owing to its vast pharmacological …

Chemical probes for free radicals in biology are important tools; fluorescence and
chemiluminescence offer high detection sensitivity. This article reviews progress in the …

The free radical nitric oxide (NO•) exerts biological effects through the direct and reversible
interaction with specific targets (eg soluble guanylate cyclase) or through the generation of …

Hydrogen sulfide (H 2 S) has emerged as an important gaseous signaling molecule that is
produced endogenously by enzymes in the sulfur metabolic network. H 2 S exerts its effects …

The development of cancer cell resistance to various cytotoxic stimuli continues to be a
major challenge in oncology and novel therapeutic approaches are urgently needed. Nitric …

Nitric oxide (NO) is a short-life molecule produced by the enzyme known as the nitric oxide
synthase (NOS), in a reaction that converts arginine and oxygen into citrulline and NO …

The synthesis, photophysical properties, and a biological application of BODIPY-triazole 1
(BOT1) are described. BOT1 juxtaposes a BODIPY fluorophore with a tripodal ligand …

Nitroxyl (HNO), the 1-electron reduced and protonated congener of nitric oxide (NO), has
received recent attention as a potential pharmacological agent for the treatment of heart …

Frustrated Lewis Pairs (FLPs) show a rapidly increasing spectrum of interesting chemical
reactions.[1] They have been reported to activate dihydrogen under mild conditions and to …