Covering: 2015 to 2020 Nitrogen heterocyclic natural products (NHNPs) are primary or
secondary metabolites containing nitrogen heterocyclic (N-heterocyclic) skeletons. Due to …

Pictet–Spenglerases provide a key role in the biosynthesis of many biologically active
alkaloids. There is increasing use of these biocatalysts as an alternative to traditional …

Diverse β-carboline (βC) alkaloids are produced by microbes, plants, and animals with
myriad bioactivities and drug potentials. However, the biosynthetic mechanism of βCs …

The Pictet-Spengler reaction (PS) is one of the most direct, efficient, and variable synthetic
method for the construction of privileged pharmacophores such as tetrahydro-isoquinolines …

β-Carbolines (βCs) are naturally occurring bioactive alkaloids, whereas α-dicarbonyl
compounds are reactive substances generated in foods and in vivo. In this work, l …

Abstract The Pictet–Spengler reaction (PSR) involves the condensation and ring closure
between a β-arylethylamine and a carbonyl compound. The combination of dopamine and …

Nitrogen-containing heterocycles (N-heterocycles) are ubiquitous in both organisms and
pharmaceutical products. Biocatalysts are providing green approaches for synthesizing …

Chemical reactions that are named in honor of their true, or at least perceived, discoverers
are known as “name reactions”. This Review is a collection of biological representatives of …

Stereoselective methods for the synthesis of tetrahydro‐ß‐carbolines are of significant
interest due to the broad spectrum of biological activity of the target molecules. In the plant …

Halogen-containing molecules are ubiquitous in modern society and present unique
chemical possibilities. As a whole, de novo fermentation and synthetic pathway construction …