Synthetic heterocyclic compounds have incredible potential against different diseases;
pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent …

Tuberculosis is still an urgent global health problem, mainly due to the spread of multi-drug
resistant M. tuberculosis strains, which lead to the need of new more efficient drugs. A …

In the present study, new tacrine derivatives containing carbamate group were synthesized
and their acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition …

A simple and efficient domino reaction has been designed and employed for the one‐pot
synthesis of N‐(hetero) aryl carbamates through the reaction between alcohols and in‐situ …

In the present study, a series of azo derivatives (TR-1 to TR-9) have been synthesised via
the diazo-coupling approach between substituted aromatic amines with phenol or naphthol …

Latent tuberculosis infection (LTBI) represents a major challenge to curing TB disease.
Current guidelines for LTBI management include only three older drugs and their …

Abstract Bioactive carbamate‐1, 4‐disubstituted 1, 2, 3‐triazole hybrid molecules were
synthesized and characterized in high yield from carbamate‐linked terminal alkynes and in …

Mycobacterium tuberculosis is an intracellular pathogen and the uptake of the
antimycobacterial compounds by host cells is limited. Novel antimycobacterials effective …

Novel antimycobacterial drugs are needed, especially those with dual activity against both
actively growing and non-replicating subpopulations of mycobacteria. Isocitrate lyase (ICL) …

Tuberculosis (TB) remains a global health crisis, further exacerbated by the slow pace of
new treatment options, and the emergence of extreme and total drug resistance to existing …