Photosensitizer nanoparticles boost photodynamic therapy for pancreatic cancer treatment

H Yang, R Liu, Y Xu, L Qian, Z Dai - Nano-Micro Letters, 2021 - Springer
Patients with pancreatic cancer (PCa) have a poor prognosis apart from the few suitable for
surgery. Photodynamic therapy (PDT) is a minimally invasive treatment modality whose …

Conjugates of porphyrinoid-based photosensitizers with cytotoxic drugs: current progress and future directions toward selective photodynamic therapy

VF Otvagin, NS Kuzmina, ES Kudriashova… - Journal of medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …

Antimicrobial and anticancer applications and related mechanisms of curcumin-mediated photodynamic treatments

QQ Yang, AK Farha, G Kim, K Gul, RY Gan… - Trends in Food Science & …, 2020 - Elsevier
Background Curcumin has gained increasing attention in recent years due to its biological
properties and photosensitivity. Curcumin-mediated photodynamic therapy has been used …

Exploring the applications of the photoprotective properties of anthocyanins in biological systems

H Oliveira, P Correia, AR Pereira, P Araújo… - International journal of …, 2020 - mdpi.com
Due to their physical and chemical characteristics, anthocyanins are amongst the most
versatile groups of natural compounds. Such unique signature makes these compounds a …

Biotin-conjugated PEGylated porphyrin self-assembled nanoparticles co-targeting mitochondria and lysosomes for advanced chemo-photodynamic combination …

B Purushothaman, J Choi, S Park, J Lee… - Journal of Materials …, 2019 - pubs.rsc.org
The combination of chemotherapy and photodynamic therapy (chemo–PDT) has been
suggested as an alternative therapy for drug-resistant cancers. In this study, biotin …

[HTML][HTML] A review of the efficacy of nanomaterial-based natural photosensitizers to overcome multidrug resistance in cancer

J Rajaram, LK Mende, Y Kuthati - Pharmaceutics, 2024 - pmc.ncbi.nlm.nih.gov
Natural photosensitizers (PS) are compounds derived from nature, with photodynamic
properties. Natural PSs have a similar action to that of commercial PSs, where cancer cell …

Curcumin: recent updates on gastrointestinal cancers

M Imran, F Saeed, SA Alsagaby, A Imran… - CyTA-Journal of …, 2023 - Taylor & Francis
Curcumin is a phenolic pigment, naturally present in Curcuma longa species. It is a yellow
active ingredient and shows a pivotal role in the modulation of biological processes resulting …

Therapeutic effect of curcumin in gastrointestinal cancers: a comprehensive review

K Morshedi, S Borran, MS Ebrahimi… - Phytotherapy …, 2021 - Wiley Online Library
Gastrointestinal (GI) cancers with a high global prevalence are a leading cause of morbidity
and mortality. Accordingly, there is a great need to develop efficient therapeutic approaches …

Multimodal polysilsesquioxane nanoparticles for combinatorial therapy and gene delivery in triple-negative breast cancer

R Juneja, Z Lyles, H Vadarevu, KA Afonin… - Therapeutic RNA …, 2021 - taylorfrancis.com
Multifunctional hybrid nanoparticles are being developed to carry a wide variety of
therapeutic and imaging agents for multiple biomedical applications. Polysilsesquioxane …

Advanced near‐infrared light‐responsive nanomaterials as therapeutic platforms for cancer therapy

YH Chien, KK Chan, T Anderson, KV Kong… - Advanced …, 2019 - Wiley Online Library
Cancer is one of the leading causes of death. Despite the huge progress in the field of
cancer drugs and therapies, the treatment outcome is still bleak for most cancer patients …