A common challenge in the analysis of genomics data is trying to understand the underlying
phenomenon in the context of all complex interactions taking place on various signaling …

The cell cycle is the cascade of events that allows a growing cell to duplicate all its
components and split into two daughter cells. Cell cycle progression is mediated by the …

The proto-oncogene Myc serves as a paradigm for understanding the dynamics of
transcriptional regulation. Myc protein has been linked to immune dysfunction, cancer …

Identification and functional analysis of novel potential cancer-associated genes is of great
importance for developing diagnostic, preventive and therapeutic strategies for cancer …

Simple Summary Colorectal cancer (CRC) is a complex disease that has a high mortality
rate. This study explored CRC-related core genes (CGs) from multiple microarray gene …

The metastatic behavior of melanoma has accentuated the need for specific therapy targets.
Compounds, namely l‐kynurenine (l‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) …

Background It is well known that carcinogenesis is in part dictated by dysregulated
transcription events and signal pathways. Large-scale transcriptional profiling studies in …

Lung cancer is the most common cause of cancer-related death in the world. The main types
of lung cancer are small cell lung carcinoma (SCLC) and non-small-cell lung carcinoma …

As one of the most common malignancies in the world, lung adenocarcinoma (LUAD) is
currently difficult to cure. However, the advent of precision medicine provides an opportunity …

Pathway analysis is a common approach to gain insight from biological experiments.
Signaling-pathway impact analysis (SPIA) is one such method and combines both the …