High-throughput routes to biomaterials discovery
F Soheilmoghaddam, M Rumble… - Chemical …, 2021 - ACS Publications
Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …
or lost tissue and organ function, an unenviable situation only further exacerbated by a …
Local nascent protein deposition and remodelling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels
Hydrogels serve as valuable tools for studying cell–extracellular matrix interactions in three-
dimensional environments that recapitulate aspects of native extracellular matrix. However …
dimensional environments that recapitulate aspects of native extracellular matrix. However …
Supramolecular host–guest hydrogels for corneal regeneration
AC Madl, D Myung - Gels, 2021 - mdpi.com
Over 6.2 million people worldwide suffer from moderate to severe vision loss due to corneal
disease. While transplantation with allogenic donor tissue is sight-restoring for many …
disease. While transplantation with allogenic donor tissue is sight-restoring for many …
Harnessing the secreted extracellular matrix to engineer tissues
Harnessing the secreted extracellular matrix to engineer tissues | Nature Biomedical Engineering
Skip to main content Thank you for visiting nature.com. You are using a browser version with …
Skip to main content Thank you for visiting nature.com. You are using a browser version with …
Evaluation of techniques used for visualisation of hydrogel morphology and determination of pore size distributions
This study evaluated three techniques, stimulated emission depletion (STED) microscopy,
atomic force microscopy (AFM), and cryogenic scanning electron microscopy (Cryo-SEM) …
atomic force microscopy (AFM), and cryogenic scanning electron microscopy (Cryo-SEM) …
Extracellular matrix production by mesenchymal stromal cells in hydrogels facilitates cell spreading and is inhibited by FGF‐2
In native tissues, the interaction between cells and the surrounding extracellular matrix
(ECM) is reciprocal, as cells not only receive signals from the ECM but also actively remodel …
(ECM) is reciprocal, as cells not only receive signals from the ECM but also actively remodel …
Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels
Human induced pluripotent stem cell (iPSC)-derived alveolar organoids have emerged as a
system to model the alveolar epithelium in homeostasis and disease. However, alveolar …
system to model the alveolar epithelium in homeostasis and disease. However, alveolar …
Improvement of Mesenchymal Stromal Cell Proliferation and Differentiation via Decellularized Extracellular Matrix on Substrates With a Range of Surface Chemistries
MC Yang, AJ O'Connor, B Kalionis… - Frontiers in Medical …, 2022 - frontiersin.org
Decellularized extracellular matrix (dECM) deposited by mesenchymal stromal cells (MSCs)
has emerged as a promising substrate for improved expansion of MSCs. To date, essentially …
has emerged as a promising substrate for improved expansion of MSCs. To date, essentially …
Stem cell extracellular matrix-modified decellularized tendon slices facilitate the migration of bone marrow mesenchymal stem cells
X Yao, LJ Ning, SK He, J Cui, RN Hu… - ACS Biomaterials …, 2019 - ACS Publications
It is highly desirable to develop a novel scaffold that can induce stem cell migration in
tendon tissue engineering and regeneration. The objective of this study is to assess the …
tendon tissue engineering and regeneration. The objective of this study is to assess the …
Synthesis and Photopatterning of Synthetic Thiol-Norbornene Hydrogels
US Jalloh, A Gsell, KA Gultian, J MacAulay, A Madden… - Gels, 2024 - mdpi.com
Hydrogels are a class of soft biomaterials and the material of choice for a myriad of
biomedical applications due to their biocompatibility and highly tunable mechanical and …
biomedical applications due to their biocompatibility and highly tunable mechanical and …