This paper reviews the process of elimination of creatinine (CRE), and the limitations
presented when using it to express urine concentrations. This literature review leads to three …

Glomerular hyperfiltration and albuminuria are two pathological conditions that could alter
renal drug elimination, but they have been rarely studied in a critical care setting. The aims …

Assessment of renal function in critically ill patients is important for appropriate
individualization of dosage regimens and nutrition, but is complicated by a high incidence of …

Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury
(AKI), but their categorical rather than continuous nature restricts their use to a research tool …

Introduction: Creatinine concentration in plasma has been used to evaluate renal function.
However, the endogenous creatinine clearance (CrCl) is more sensitive to this goal …

The accuracy of 2‐and 8‐hour urine collections for estimating creatinine clearance was
compared with that of the standard 24‐hour procedure in 45 hospitalized elderly patients …

Objective and rationale To investigate if the 2-h creatinine clearance (Ccr 2) provides a more
precise and timely assessment of renal function in critically ill patients compared to the …

INTRODUÇÃO: A concentração da creatinina no plasma é usada para avaliar a função
renal, mas a depuração da creatinina plasmática (DCP) constitui método mais sensível para …

The accuracy of creatinine clearance estimations obtained from 4‐hour (16: 00‐20: 00, 20:
00‐24: 00, 08: 00‐12: 00, 12: 00‐16: 00) and 8‐hour (16: 00‐24: 00, 24: 00‐08: 00 and 08 …

Background and objective Augmented renal clearance or glomerular hyperfiltration (GHF)
can significantly affect the clinical outcomes of renally eliminated drugs by promoting …