Immunopathogenesis of IBD: current state of the art

HSP De Souza, C Fiocchi - Nature reviews Gastroenterology & …, 2016 - nature.com
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes

S Singh, PS Dulai, A Zarrinpar… - Nature reviews …, 2017 - nature.com
Incidence of IBD is rising in parallel with overweight and obesity. Contrary to conventional
belief, about 15–40% of patients with IBD are obese, which might contribute to the …

Inclusion of the mesentery in ileocolic resection for Crohn's disease is associated with reduced surgical recurrence

CJ Coffey, MG Kiernan, SM Sahebally… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Inclusion of the mesentery during resection for colorectal
cancer is associated with improved outcomes but has yet to be evaluated in Crohn's …

Location is important: differentiation between ileal and colonic Crohn's disease

R Atreya, B Siegmund - Nature Reviews Gastroenterology & …, 2021 - nature.com
Crohn's disease can affect any part of the gastrointestinal tract; however, current European
and national guidelines worldwide do not differentiate between small-intestinal and colonic …

Multidimensional impact of Mediterranean diet on IBD patients

F Chicco, S Magrì, A Cingolani… - Inflammatory bowel …, 2021 - academic.oup.com
Abstract Background & Aims Malnutrition with the accumulation of fat tissue and
nonalcoholic fatty liver disease (NAFLD) are conditions associated with inflammatory bowel …

Risk for lower intestinal perforations in patients with rheumatoid arthritis treated with tocilizumab in comparison to treatment with other biologic or conventional …

A Strangfeld, A Richter, B Siegmund… - Annals of the …, 2017 - ard.bmj.com
Objective To investigate the risk of developing lower intestinal perforations (LIPs) in patients
with rheumatoid arthritis (RA) treated with tocilizumab (TCZ). Methods In 13 310 patients …

Bioactive factors in human breast milk attenuate intestinal inflammation during early life

JD Thai, KE Gregory - Nutrients, 2020 - mdpi.com
Human breast milk is well known as the ideal source of nutrition during early life, ensuring
optimal growth during infancy and early childhood. Breast milk is also the source of many …

[HTML][HTML] Obesity is associated with increased risk of Crohn's disease, but not ulcerative colitis: a pooled analysis of five prospective cohort studies

SSM Chan, Y Chen, K Casey, O Olen… - Clinical …, 2022 - Elsevier
Background and Aims It is unclear whether obesity is associated with the development of
inflammatory bowel disease despite compelling data from basic science studies. We …

Role of gut microbiota in Crohn's disease pathogenesis: Insights from fecal microbiota transplantation in mouse model

Q Wu, LW Yuan, LC Yang, YW Zhang… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Inflammatory bowel disease, particularly Crohn's disease (CD), has been
associated with alterations in mesenteric adipose tissue (MAT) and the phenomenon termed …

Adipose tissue immune response: novel triggers and consequences for chronic inflammatory conditions

G Ghigliotti, C Barisione, S Garibaldi, P Fabbi… - Inflammation, 2014 - Springer
Adipose tissue inflammation mediates the association between excessive body fat
accumulation and several chronic inflammatory diseases. A high prevalence of obesity …