Rodent models for human polycystic ovary syndrome

KA Walters, CM Allan, DJ Handelsman - Biology of reproduction, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is the most frequent female endocrine disorder, affecting
5%–10% of women, causing infertility due to dysfunctional follicular maturation and …

[HTML][HTML] A landscape analysis of the potential role of polyphenols for the treatment of Polycystic Ovarian Syndrome (PCOS)

R Rani, YA Hajam, R Kumar, RA Bhat, S Rai… - Phytomedicine Plus, 2022 - Elsevier
Abstract Background Polycystic Ovarian Syndrome (PCOS) is an under-recognized, under-
diagnosed and under-studied disorder; its prevalence varies between 5–26%, 6–10% of …

Characterization of reproductive, metabolic, and endocrine features of polycystic ovary syndrome in female hyperandrogenic mouse models

ASL Caldwell, LJ Middleton, M Jimenez, R Desai… - …, 2014 - academic.oup.com
Polycystic ovary syndrome (PCOS) affects 5–10% of women of reproductive age, causing a
range of reproductive, metabolic and endocrine defects including anovulation, infertility …

[HTML][HTML] Beneficial effect of Curcumin in Letrozole induced polycystic ovary syndrome

PS Reddy, N Begum, S Mutha, V Bakshi - Asian Pacific Journal of …, 2016 - Elsevier
Objective To investigated beneficial effect of Curcumin (a phenolic curcuminoid derivative
from Curcuma longa) in Letrozole induced PCOS in female Wistar rats. Methods Letrozole (1 …

Therapeutic potentials of Quercetin in management of polycystic ovarian syndrome using Letrozole induced rat model: a histological and a biochemical study

S Jahan, A Abid, S Khalid, T Afsar, G Shaheen… - Journal of ovarian …, 2018 - Springer
Background PCOS is a leading endocrinopathy of young women instigating androgens
elevation, insulin resistance, obesity, cardiometabolic and menstrual complications. The …

Apigenin exerts protective effect and restores ovarian function in dehydroepiandrosterone induced polycystic ovary syndrome rats: a biochemical and histological …

F Peng, Y Hu, S Peng, N Zeng, L Shi - Annals of Medicine, 2022 - Taylor & Francis
Background Polycystic ovarian syndrome (PCOS) is one of the major causes encouraging
the elevation of androgens, obesity along with menstrual complications. Here we study the …

[HTML][HTML] Turmeric extract alleviates endocrine-metabolic disturbances in letrozole-induced PCOS by increasing adiponectin circulation: A comparison with Metformin

VK Shrivastava - Metabolism open, 2022 - Elsevier
One of the most common causes of female infertility is polycystic ovarian syndrome, which
affects 6–21% of the population. Regrettably, the currently available treatments are mostly …

Thuja occidentalis L. and its active compound, α-thujone: Promising effects in the treatment of polycystic ovary syndrome without inducing osteoporosis

EK Akkol, M İlhan, MA Demirel, H Keleş, I Tümen… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Thuja occidentalis L.(Cupressaceae) has been used in
folk medicine for the treatment of rheumatism, amenorrhea, cystitis, and uterine carcinomas …

Experimental models of polycystic ovary syndrome: An update

S Divyashree, P Janhavi, PV Ravindra… - Life sciences, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is one of the major endocrine disorders in women. PCOS
is a disorder with alterations in the structure as well as functions of female reproductive …

Histomorphometric and biochemical activities of bioactive component of Cyperus esculentus tubers extract on letrozole-induced polycystic ovarian syndrome and …

SA Adelakun, AO Ojewale, SO Jeje… - Toxicology Research …, 2022 - journals.sagepub.com
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disorder,
causes irregular menstrual cycles, dyslipidemia, excessive body weight, oxidative stress …