Mesenchymal stem (stromal) cells (MSCs) are rare, multipotent progenitor cells that can be
isolated and expanded from bone marrow and other tissues. Strikingly, MSCs modulate the …

Wharton's jelly (WJ) is a gelatinous tissue within the umbilical cord that contains
myofibroblast-like stromal cells. A unique cell population of WJ that has been suggested as …

To dissect therapeutic mechanisms of transplanted stem cells and develop exosome-based
nanotherapeutics in treating autoimmune and neurodegenerative diseases, we assessed …

Introduction 'Patient-specific'induced pluripotent stem cells (iPSCs) are attractive because
they can generate abundant cells without the risk of immune rejection for cell therapy …

Objectives To evaluate the safety and tolerability of the intravenous administration of Cx611,
a preparation of allogeneic expanded adipose-derived stem cells (eASCs), in patients with …

Purpose The management of perianal fistula in patients with Crohn's disease is an
extremely challenging medical problem as many fistulas do not respond to available …

Abstract Tissue-engineered skin (TES), as an analogue of native skin, is promising for
wound repair and regeneration. However, a major drawback of TES products is a lack of …

Introduction The ability to self-renew, be easily expanded in vitro and differentiate into
different mesenchymal tissues, render mesenchymal stem cells (MSCs) an attractive …

Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell
therapy by the European Medicines Agency. The authorization concerns the use of …

Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …