The DNA methylation landscape in cancer

K Skvortsova, C Stirzaker, P Taberlay - Essays in biochemistry, 2019 - portlandpress.com
As one of the most abundant and well-studied epigenetic modifications, DNA methylation
plays an essential role in normal development and cellular biology. Global alterations to the …

DNA methylation analysis: choosing the right method

S Kurdyukov, M Bullock - Biology, 2016 - mdpi.com
In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …

State-of-the-art survey of artificial intelligent techniques for IoT security

TA Ahanger, A Aljumah, M Atiquzzaman - Computer Networks, 2022 - Elsevier
The data protection problem concerning the Internet of Things (IoT) paradigm has drawn the
innovation community's considerable attention. Several surveys have covered different IoT …

[HTML][HTML] Acute exercise remodels promoter methylation in human skeletal muscle

R Barres, J Yan, B Egan, JT Treebak, M Rasmussen… - Cell metabolism, 2012 - cell.com
DNA methylation is a covalent biochemical modification controlling chromatin structure and
gene expression. Exercise elicits gene expression changes that trigger structural and …

Cigarette smoking and DNA methylation

KWK Lee, Z Pausova - Frontiers in genetics, 2013 - frontiersin.org
DNA methylation is the most studied epigenetic modification, capable of controlling gene
expression in the contexts of normal traits or diseases. It is highly dynamic during early …

Non-CpG methylation of the PGC-1α promoter through DNMT3B controls mitochondrial density

R Barrès, ME Osler, J Yan, A Rune, T Fritz, K Caidahl… - Cell metabolism, 2009 - cell.com
Epigenetic modification through DNA methylation is implicated in metabolic disease. Using
whole-genome promoter methylation analysis of skeletal muscle from normal glucose …

[HTML][HTML] Cell surface mechanics gate embryonic stem cell differentiation

M Bergert, S Lembo, S Sharma, L Russo… - Cell Stem Cell, 2021 - cell.com
Cell differentiation typically occurs with concomitant shape transitions to enable specialized
functions. To adopt a different shape, cells need to change the mechanical properties of their …

Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits

CCY Wong, EL Meaburn, A Ronald, TS Price… - Molecular …, 2014 - nature.com
Autism spectrum disorder (ASD) defines a group of common, complex neurodevelopmental
disorders. Although the aetiology of ASD has a strong genetic component, there is …

DNA methylation analysis by pyrosequencing

J Tost, IG Gut - Nature protocols, 2007 - nature.com
Pyrosequencing is a sequencing-by-synthesis method that quantitatively monitors the real-
time incorporation of nucleotides through the enzymatic conversion of released …

An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training

ME Lindholm, F Marabita, D Gomez-Cabrero… - Epigenetics, 2014 - Taylor & Francis
Regular endurance exercise training induces beneficial functional and health effects in
human skeletal muscle. The putative contribution to the training response of the epigenome …