Metalated covalent organic frameworks: from synthetic strategies to diverse applications

Q Guan, LL Zhou, YB Dong - Chemical Society Reviews, 2022 - pubs.rsc.org
Covalent organic frameworks (COFs) are a class of organic crystalline porous materials
discovered in the early 21st century that have become an attractive class of emerging …

Polyprodrug nanomedicines: an emerging paradigm for cancer therapy

K Yang, Z Yang, G Yu, Z Nie, R Wang… - Advanced …, 2022 - Wiley Online Library
Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …

Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles

M Souri, M Soltani, FM Kashkooli… - Journal of Controlled …, 2022 - Elsevier
Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …

Cation‐free siRNA micelles as effective drug delivery platform and potent RNAi nanomedicines for glioblastoma therapy

T Jiang, Y Qiao, W Ruan, D Zhang, Q Yang… - Advanced …, 2021 - Wiley Online Library
Nanoparticle‐based small interfering RNA (siRNA) therapy shows great promise for
glioblastoma (GBM). However, charge associated toxicity and limited blood–brain‐barrier …

Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches

S Ghosh, A Javia, S Shetty, D Bardoliwala… - Journal of Controlled …, 2021 - Elsevier
Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …

[HTML][HTML] Antimicrobial activity of nanoformulations of carvacrol and thymol: New trend and applications

A Hajibonabi, M Yekani, S Sharifi, JS Nahad, SM Dizaj… - OpenNano, 2023 - Elsevier
Thymol and carvacrol are aromatic compounds derived from plants that exhibit considerable
broad-spectrum antimicrobial effects. They have also shown extensive biological effects …

Advancements in redox-sensitive micelles as nanotheranostics: a new horizon in cancer management

A Sikder, G Vambhurkar, E Amulya… - Journal of Controlled …, 2022 - Elsevier
Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …

Bispecific antibodies for targeted delivery of anti-cancer therapeutic agents: a review

A Beishenaliev, YL Loke, SJ Goh, HN Geo… - Journal of Controlled …, 2023 - Elsevier
Monospecific antibodies have been utilised increasingly for anti-cancer drug targeting owing
to their ability to minimise off-target toxicity by binding specifically to a tumour epitope, hence …

Chitosan-coated-PLGA nanoparticles enhance the antitumor and antimigration activity of stattic–a STAT3 dimerization blocker

SS Fong, YY Foo, WS Saw, BF Leo… - International Journal …, 2022 - Taylor & Francis
Purpose The use of nanocarriers to improve the delivery and efficacy of antimetastatic
agents is less explored when compared to cytotoxic agents. This study reports the …

Ferroptosis in cancer therapeutics: a materials chemistry perspective

Q Guan, LL Zhou, YB Dong - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Ferroptosis, distinct from apoptosis, is a regulated form of cell death caused by lipid
peroxidation that has attracted extensive research interest since it was first defined in 2012 …