The development of ambient ionization mass spectrometry (AIMS) has transformed
analytical science, providing the means of performing rapid analysis of samples in their …

Miniaturization of the analytical process has been a widespread trend, and the sample
preparation stage is not exempted from this downscaling. Since the introduction of …

This study proposes a hypodermic needle (HN) as a sorbent holder and an electrospray
(ESI) emitter, thus combining extraction and analysis in a single device. A novel nylon 6 …

Direct mass spectrometry (MS) is an exciting strategy in bioanalysis, enabling rapid decision-
making in different scenarios. Its application is usually hindered by matrix effects and the …

Background Opioids are effective painkillers used for medical purposes. Their prolonged
ingestion can provoke some side effects (including overdose or constipation) that are …

This article describes the synthesis of mixed-mode cationic exchange (MCX) tapes as
sorptive phases in bioanalysis, and it faces the determination of methadone and tramadol in …

Sample preparation is a constantly evolving step in the measurement process with a positive
effect on its performance. Its evolution has been marked by an underlying environmental …

Direct coupling of sample preparation with mass spectrometry (MS) can speed up analysis,
enabling faster decision-making. In such combinations, where the analysis time is mainly …

The use of natural materials as precursors for synthesizing sorptive phases can reduce the
environmental impact of the sample preparation step. In this article, two natural materials, ie …

Miniature mass spectrometers are in a phase of rapid development due to their potential in
offering simple yet powerful solutions for a wide variety of unmet biomedical needs. In …