Medicinal plants are the main source of active chemical constituents responsible for curing or mitigating various ailments. To discover new, safe, and effective drug candidates the …
MN Rocha, DR Alves, MM Marinho… - Journal of …, 2021 - World Scientific
It is of great importance for the pharmaceutical industry to find therapeutic substances extracted from natural sources, which are abundant, obtained with low costs and presenting …
Several α-ketoamides from natural as well as synthetic sources have been shown to possess multitude of biological activities due to their versatile nature and presence of …
Dengue fever is a serious disease acquired from the Aedes aegypti mosquito present in tropical and subtropical regions, deeply impacting the population's quality of life. Its control …
In the present work, we have calculated the electrical and optical properties of pure piceatannol (PI) and its six fluorinated derivatives (F1-F6). The first-principles calculations …
In the current era, a potent drug is still needed on the market for the treatment of various diseases worldwide. Researchers mainly focus on those enzymes that cause these …
G Tataringa, C Tuchilus, M Ahmed, S Ahmed… - Bioorganic …, 2024 - Elsevier
This synthetic organic methodology involves the creation of novel coumarin-based hybrids of series (1–4) with pyrazole ring and (5–8) with oxadiazole moiety. The targeted …
Obesity represents a significant global health issue that continues to escalate in prevalence. Interestingly, there is a less explored connection between obesity and compromised leptin …
In this study, the syntheses of some pyrazole-thiazole hybrids and their cyanoacrylate derivatives have been reported. 1 H NMR, 13 C NMR, LC-MS, and IR spectroscopy were …