Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

MB Hansen, SE Nielsen, K Berg - Journal of immunological methods, 1989 - Elsevier
The tetrazolium salt (MTT) method involving conversion of MTT to coloured formazan by
cells serving as indirect measurements of cell growth/cell kill has been reported by several …

IL-28, IL-29 and their class II cytokine receptor IL-28R

P Sheppard, W Kindsvogel, W Xu, K Henderson… - Nature …, 2003 - nature.com
Cytokines play a critical role in modulating the innate and adaptive immune systems. Here,
we have identified from the human genomic sequence a family of three cytokines …

Lambda interferon (IFN-λ), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo

N Ank, H West, C Bartholdy, K Eriksson… - Journal of …, 2006 - Am Soc Microbiol
Type III interferons (IFNs)(interleukin-28/29 or lambda interferon [IFN-λ]) are cytokines with
IFN-like activities. Here we show that several classes of viruses induce expression of IFN-λ1 …

Hydrogen peroxide–and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells

SW Ballinger, C Patterson, CN Yan, R Doan… - Circulation …, 2000 - Am Heart Assoc
The mechanisms by which reactive species (RS) participate in the development of
atherosclerosis remain incompletely understood. The present study was designed to test the …

Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells

SW BALLINGER, B VAN HOUTEN, CA CONKLIN… - Experimental eye …, 1999 - Elsevier
Retinal pigment epithelial cell dysfunction mediated by reactive oxygen intermediates has
been suggested as a possible cause of age-related macular degeneration. To test the …

Cytotoxicity of mycotoxins evaluated by the MTT-cell culture assay

M Hanelt, M Gareis, B Kollarczik - Mycopathologia, 1994 - Springer
The application of a modified colorimetric bioassay for the evaluation of the biological effects
of mycotoxins is reported. Using three different monolayer cell lines (swine kidney, Madin …

Hydroxyapatite nanoparticles as a novel gene carrier

SH Zhu, BY Huang, KC Zhou, SP Huang, F Liu… - Journal of Nanoparticle …, 2004 - Springer
Hydroxyapatite crystalline nanoparticles were created by a precipitation hydrothermal
technique and the majority of crystal particles were in the size range of 40–60nm and …

[HTML][HTML] Assessment of food toxicology

A Gosslau - Food Science and Human Wellness, 2016 - Elsevier
The interest in food toxicology is evident by the dependency of humankind on nutrition by
virtue of their heterotrophic metabolism. By means of modern biochemistry, molecular and …

Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells

S Page, A Munsell, AJ Al-Ahmad - Fluids and Barriers of the CNS, 2016 - Springer
Background Cerebral hypoxia/ischemia (H/I) is an important stress factor involved in the
disruption of the blood–brain barrier (BBB) following stroke injury, yet the cellular and …

The pattern and level of cytokines secreted by Th1 and Th2 lymphocytes of syphilitic patients correlate to the progression of the disease

J Podwinska, M Lusiak, R Zaba… - FEMS Immunology & …, 2000 - academic.oup.com
The results of our previous work indicated that cell-mediated immune response, of
importance in protection against Treponema pallidum, is distinctly inhibited at certain …