The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

[HTML][HTML] Nanoparticle biodistribution coefficients: A quantitative approach for understanding the tissue distribution of nanoparticles

M Kumar, P Kulkarni, S Liu, N Chemuturi… - Advanced Drug Delivery …, 2023 - Elsevier
The objective of this manuscript is to provide quantitative insights into the tissue distribution
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …

Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach

YH Cheng, C He, JE Riviere, NA Monteiro-Riviere… - ACS …, 2020 - ACS Publications
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …

Recent advances in superparamagnetic iron oxide nanoparticles (SPIONs) for in vitro and in vivo cancer nanotheranostics

G Kandasamy, D Maity - International journal of pharmaceutics, 2015 - Elsevier
Recently superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used
in cancer therapy and diagnosis (theranostics) via magnetic targeting, magnetic resonance …

Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics

S Goel, CG England, F Chen, W Cai - Advanced drug delivery reviews, 2017 - Elsevier
Abstract Development of novel imaging probes for cancer diagnosis is critical for early
disease detection and management. The past two decades have witnessed a surge in the …

Nanoparticle functionalization and its potentials for molecular imaging

R Thiruppathi, S Mishra, M Ganapathy… - Advanced …, 2017 - Wiley Online Library
Functionalization enhances the properties and characteristics of nanoparticles through
surface modification, and enables them to play a major role in the field of medicine. In …

Biodistribution and targeting properties of iron oxide nanoparticles for treatments of cancer and iron anemia disease

E Alphandéry - Nanotoxicology, 2019 - Taylor & Francis
IONP (iron oxide nanoparticles) commercialized for treatments of iron anemia or cancer
diseases can be administered at doses exceeding 1 g per patient, indicating their bio …

The role of magnetic nanoparticles in cancer nanotheranostics

M Ferreira, J Sousa, A Pais, C Vitorino - Materials, 2020 - mdpi.com
Technological development is in constant progress in the oncological field. The search for
new concepts and strategies for improving cancer diagnosis, treatment and outcomes …

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

L Farzin, S Sheibani, ME Moassesi… - Journal of Biomedical …, 2019 - Wiley Online Library
Recent advances in the field of nanotechnology applications in nuclear medicine offer the
promise of better diagnostic and therapeutic options. In recent years, increasing efforts have …