The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain

A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Normal aging induces changes in the brain and neurodegeneration progress: review of the structural, biochemical, metabolic, cellular, and molecular changes

J Lee, HJ Kim - Frontiers in aging neuroscience, 2022 - frontiersin.org
Aging is accompanied by many changes in brain and contributes to progressive cognitive
decline. In contrast to pathological changes in brain, normal aging brain changes have …

Motor control and aging: links to age-related brain structural, functional, and biochemical effects

RD Seidler, JA Bernard, TB Burutolu, BW Fling… - Neuroscience & …, 2010 - Elsevier
Although connections between cognitive deficits and age-associated brain differences have
been elucidated, relationships with motor performance are less well understood. Here, we …

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

W Shao, S Zhang, M Tang, X Zhang, Z Zhou, Y Yin… - Nature, 2013 - nature.com
Chronic neuroinflammation is a common feature of the ageing brain and some
neurodegenerative disorders. However, the molecular and cellular mechanisms underlying …

A meta-analytic review of emotion recognition and aging: Implications for neuropsychological models of aging

T Ruffman, JD Henry, V Livingstone… - … & Biobehavioral Reviews, 2008 - Elsevier
This meta-analysis of 28 data sets (N= 705 older adults, N= 962 younger adults) examined
age differences in emotion recognition across four modalities: faces, voices, bodies/contexts …

Aging cognition: from neuromodulation to representation

SC Li, U Lindenberger, S Sikström - Trends in cognitive sciences, 2001 - cell.com
Basic cognitive functions, such as the abilities to activate, represent, maintain, focus and
process information, decline with age. A paradigm shift towards cross-level conceptions is …

[PDF][PDF] Frontal lobes and aging: deterioration and compensation

R Cabeza, NA Dennis - Principles of frontal lobe function, 2012 - cabezalab.org
Until the mid 1990s, available evidence regarding neurocognitive aging could be
summarized in a simple statement: cognitive deficits in healthy older adults are largest for …

The correlative triad among aging, dopamine, and cognition: current status and future prospects

L Bäckman, L Nyberg, U Lindenberger, SC Li… - Neuroscience & …, 2006 - Elsevier
The brain neuronal systems defined by the neurotransmitter dopamine (DA) have since long
a recognized role in the regulation of motor functions. More recently, converging evidence …

Dual-tasking postural control: aging and the effects of cognitive demand in conjunction with focus of attention

O Huxhold, SC Li, F Schmiedek, U Lindenberger - Brain research bulletin, 2006 - Elsevier
Postural control in everyday life is generally accompanied by posture-unrelated cognitive
activity. Thus, mild forms of dual-tasking postural control are the norm rather than the …