Animal models of acute and chronic pancreatitis have been created to examine mechanisms
of pathogenesis, test therapeutic interventions, and study the influence of inflammation on …

Acute pancreatitis is a potentially severe inflammatory disease that may be associated with a
substantial morbidity and mortality. Currently there is no specific treatment for the disease …

Background & Aims Little is known about the signaling pathways that initiate and promote
acute pancreatitis (AP). The pathogenesis of AP has been associated with abnormal …

Recent findings from our group, obtained on experimental in vivo and ex vivo models of
pancreatitis, reveal that this disease causes a profound dysfunction of key cellular …

Animal models are ideal to study the pathomechanism and therapy of acute pancreatitis
(AP). The use of L-arginine-induced AP model is nowadays becoming increasingly popular …

Animal models of pancreatitis are useful for elucidating the pathogenesis of pancreatitis and
developing and testing novel interventions. In this review, we aim to summarize the most …

The budding yeast, Saccharomyces cerevisiae, has been used for decades as a powerful
genetic tool to study a broad spectrum of biological topics. With its ease of use, economic …

Acute pancreatitis is characterized by necrosis of its parenchymal cells and influx and
activation of inflammatory cells that further promote injury and necrosis. This review is …

Introduction Acute pancreatitis (AP) is an inflammatory disease with no specific treatment.
Mitochondrial injury followed by ATP depletion in both acinar and ductal cells is a recently …

Acute pancreatitis is an inflammatory disease with no specific treatment. One of the main
reasons behind the lack of specific therapy is that the pathogenesis of acute pancreatitis is …