Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents
Photodynamic therapy (PDT) combines a photosensitiser, light and molecular oxygen to
induce oxidative stress that can be used to kill pathogens, cancer cells and other highly …
induce oxidative stress that can be used to kill pathogens, cancer cells and other highly …
BODIPYs in PDT: a journey through the most interesting molecules produced in the last 10 years
MC Malacarne, MB Gariboldi, E Caruso - International Journal of …, 2022 - mdpi.com
Over the past 30 years, photodynamic therapy (PDT) has shown great development. In the
clinical setting the few approved molecules belong almost exclusively to the porphyrin …
clinical setting the few approved molecules belong almost exclusively to the porphyrin …
Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy
Y Lin, T Zhou, R Bai, Y Xie - Journal of enzyme inhibition and …, 2020 - Taylor & Francis
With the development of photodynamic therapy (PDT), remarkable studies have been
conducted to generate photosensitisers (PSs), especially porphyrin PSs. A variety of …
conducted to generate photosensitisers (PSs), especially porphyrin PSs. A variety of …
Synthesis and elucidation of strained galactopyronose esters as selective cyclooxygenase-2 inhibitor: a comprehensive computational approach
Cyclooxygenase-2 (COX-2) is critically implicated in various pathologies, including
inflammation, cancer, disorders involving the nervous system, and multidrug resistance. In …
inflammation, cancer, disorders involving the nervous system, and multidrug resistance. In …
Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease
Based on the quantitative structure-activity relationship (QSAR), some novel p-
aminobenzoic acid derivatives as promising cholinesterase enzyme inhibitors were …
aminobenzoic acid derivatives as promising cholinesterase enzyme inhibitors were …
Bayesian Network Resource for Meta‐Analysis: Cellular Toxicity of Quantum Dots
A web‐based resource for meta‐analysis of nanomaterials toxicity is developed whereby the
utility of Bayesian networks (BNs) is illustrated for exploring the cellular toxicity of Cd …
utility of Bayesian networks (BNs) is illustrated for exploring the cellular toxicity of Cd …
Structure based virtual screening, 3D-QSAR, molecular dynamics and ADMET studies for selection of natural inhibitors against structural and non-structural targets of …
The transmission of mosquito-borne Chikungunya virus (CHIKV) has large epidemics
worldwide. Till date, there are neither anti-viral drugs nor vaccines available for the …
worldwide. Till date, there are neither anti-viral drugs nor vaccines available for the …
Organic structure and solid characteristics determine reactivity of phenolic compounds with synthetic and reclaimed manganese oxides
EL Trainer, M Ginder-Vogel… - … Science: Water Research …, 2020 - pubs.rsc.org
Manganese (Mn) oxides have been proposed for in situ treatment of organic (eg, phenolic)
contaminants, although little is known about the reactivity of reclaimed solids that might be …
contaminants, although little is known about the reactivity of reclaimed solids that might be …
Unsupervised machine learning, QSAR modelling and web tool development for streamlining the lead identification process of antimalarial flavonoids
Identification of lead compounds with the traditional laboratory approach is expensive and
time-consuming. Nowadays, in silico techniques have emerged as a promising approach for …
time-consuming. Nowadays, in silico techniques have emerged as a promising approach for …
In silico study of liquid smoke rice husk against COVID-19
Objectives Liquid smoke rice husk has been researched and proved to consist of
antibacterial, analgesic, anti-inflammatory, and growth factor stimulatory properties. By these …
antibacterial, analgesic, anti-inflammatory, and growth factor stimulatory properties. By these …