Interoception refers to the perception of the internal state of the body and is increasingly
being recognized as an important factor in mental health disorders. Drugs of abuse produce …

Posttraumatic stress disorder (PTSD) is a prevalent and highly disabling disorder, but there
is currently no targeted pharmacological treatment for it. Dysfunction of the glutamate system …

Glutamate signaling in the brain is one of the most studied targets in the alcohol research
field. Here, we report the current understanding of how the excitatory neurotransmitter …

The cortical-striatal brain circuitry is heavily implicated in drug-use. As such, the present
study investigated the functional role of cortical-striatal circuitry in modulating alcohol self …

Postpartum depression (PPD) is a common complication following childbirth experienced by
one in every five new mothers. Pregnancy stress enhances vulnerability to PPD and has …

The nucleus accumbens core (AcbC) is a key brain region known to regulate the
discriminative stimulus/interoceptive effects of alcohol. As such, the goal of the present work …

Developing efficacious treatments for alcohol use disorder (AUD) has proven difficult. The
insidious nature of the disease necessitates a deep understanding of its underlying biology …

Identifying novel treatments that facilitate extinction learning could enhance cue-exposure
therapy and reduce high relapse rates in alcoholics. Activation of mGlu5 receptors in the …

Post-traumatic stress disorder (PTSD) is a psychiatric illness that can increase the risk for
developing an alcohol use disorder (AUD). While clinical data has been useful in identifying …

Stress and tobacco smoking are risk factors for alcoholism, but the underlying neural
mechanisms are not well understood. Although stress, nicotine, and alcohol have broad …