Molecular models of voltage sensing
CS Gandhi, EY Isacoff - The Journal of general physiology, 2002 - rupress.org
Voltage-gated ion channels have always been overachievers. They have the singular
distinction of having solved the permeation problem five times over. Not only do they have a …
distinction of having solved the permeation problem five times over. Not only do they have a …
The principle of gating charge movement in a voltage-dependent K+ channel
The steep dependence of channel opening on membrane voltage allows voltage-dependent
K+ channels to turn on almost like a switch. Opening is driven by the movement of gating …
K+ channels to turn on almost like a switch. Opening is driven by the movement of gating …
The search is on for the voltage sensor-to-gate coupling
HP Larsson - The Journal of general physiology, 2002 - rupress.org
Hodgkin and Huxley (1952) demonstrated the presence of voltage-activated sodium (Na)
and potassium (K) permeabilities in the squid giant axon. Ever since then, biophysicists …
and potassium (K) permeabilities in the squid giant axon. Ever since then, biophysicists …
[图书][B] Progress towards an understanding of voltage-sensing in ion channels
CS Gandhi - 2003 - search.proquest.com
The voltage-dependent opening of voltage-gated ion channels underlies the action of
electrical excitability in the cells of the nervous system, neurosecretion, and muscle …
electrical excitability in the cells of the nervous system, neurosecretion, and muscle …