[HTML][HTML] Chagas disease vaccine design: the search for an efficient Trypanosoma cruzi immune-mediated control

AE Bivona, AS Alberti, N Cerny, SN Trinitario… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Chagas disease is currently endemic to 21 Latin-American countries and has also become a
global concern because of globalization and mass migration of chronically infected …

Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine

AE Bivona, A Sánchez Alberti, MN Matos… - PLoS Neglected …, 2018 - journals.plos.org
Background Chagas disease, also known as American Trypanosomiasis, is a chronic
parasitic disease caused by the flagellated protozoan Trypanosoma cruzi that affects about …

Cruzipain and Its Physiological Inhibitor, Chagasin, as a DNA-Based Therapeutic Vaccine Against Trypanosoma cruzi

N Cerny, AE Bivona, A Sanchez Alberti… - Frontiers in …, 2020 - frontiersin.org
Chagas disease caused by the protozoan parasite Trypanosoma cruzi is endemic in 21
Latin American countries and the southern United States and now is spreading into several …

DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi

M Arce-Fonseca… - Journal of …, 2020 - Wiley Online Library
Chagas disease is a chronic and potentially lethal disorder caused by the parasite
Trypanosoma cruzi, and an effective treatment has not been developed for chronic Chagas …

Exploring the performance of Escherichia coli outer membrane vesicles as a tool for vaccine development against Chagas disease

ME Vázquez, AC Mesías, L Acuña… - Memórias do Instituto …, 2023 - SciELO Brasil
BACKGROUND Vaccine development is a laborious craftwork in which at least two main
components must be defined: a highly immunogenic antigen and a suitable delivery method …

Evaluation of pathogen P21 protein as a potential modulator of the protective immunity induced by Trypanosoma cruzi attenuated parasites

C Pérez Brandán, AC Mesias, L Acuña… - Memórias do Instituto …, 2019 - SciELO Brasil
BACKGROUND TcP21 is a ubiquitous secreted protein of Trypanosoma cruzi and its
recombinant form (rP21) promotes parasite cell invasion and acts as a phagocytosis inducer …

SARS-COV-2 RBD Oral Vaccine Boosted by Mucosal Immune Adjuvant LTB26 via DCs and B Cells Activation in Mice

Y Ma, Q Shi, Q Wang, S Chen, S Gan, C Fang, Y Shen… - bioRxiv, 2020 - biorxiv.org
Heat-labile enterotoxin B subunit (LTB) of Escherichia coli is a potential mucosal immune
adjuvant for its safety. However, the weaker adjuvant activity fails to meet the clinical …

[图书][B] Preclinical characterization of the protection and immune response elicited by immunizations with Schistosoma mansoni cathepsin B

A Ricciardi - 2017 - search.proquest.com
Schistosomiasis is a neglected tropical disease caused by freshwater flatworms. The
parasite eggs become trapped in host tissues and, as a consequence of the stimulated …