As one of the most densely innervated tissues, the dental pulp contains abundant nerve
fibres, including sensory, sympathetic and parasympathetic nerve fibres. Studies in animal …

A vital and healthy dental pulp (DP) is required for teeth to remain functional throughout a
lifespan. Appreciating its value for the tooth, the regeneration of the DP is a highly …

Tissue regeneration requires exogenous and endogenous signals, and there is increasing
evidence that the exogenous microenvironment may play an even more dominant role in the …

The dental pulp is critical for physiological vitality of the tooth, and dental pulp regeneration
has great potential for rebuilding live pulp tissue after pulp disease. Schwann cells (SCs) …

Keloids are disfiguring, hypertrophic scars with yet poorly understood pathomechanisms,
which could lead to severe functional impairments. Here we analyzed the characteristics of …

Abstract Background Both Schwann cell-derived exosomes (SC-Exos) and macrophagic
sub-phenotypes are closely related to the regeneration and repair after peripheral nerve …

Orofacial pain is a universal predicament, afflicting millions of individuals worldwide.
Research on the molecular mechanisms of orofacial pain has predominately focused on the …

Caries results in the demineralization and destruction of enamel and dentine, and as the
disease progresses, irreversible pulpitis can occur. Vital pulp therapy (VPT) is directed …

Introduction Molecular diagnosis may overcome the limitations of clinical and histologic
diagnosis in pulpitis, thereby benefiting many treatment techniques, such as vital pulp …

Rodent animal models for vital pulp therapy are commonly used in dental research because
their tooth anatomy and cellular processes are similar to the anatomy and processes in …