Instrumentation for positron emission tomography (PET) imaging has experienced
tremendous improvements in performance over the past 60 years since it was first conceived …

The extensive development of image fusion techniques over the past 20 y has shown that
the fusion of images from complementary modalities offers a more complete and accurate …

Abstract Time-of-flight (TOF) measurement capability promises to improve PET image
quality. We characterized the physical and clinical PET performance of the first Biograph …

Historically, medical devices to image either anatomical structure or functional processes
have developed along somewhat independent paths. The recognition that combining …

We evaluated the performance characteristics of the eXplore VISTA dual-ring small-animal
PET scanner, a stationary, ring-type, depth-of-interaction (DOI) correcting system designed …

Accurate anatomical localization of functional abnormalities obtained with the use of
positron emission tomography (PET) is known to be problematic. Although tracers such as …

Emission computed tomography (ECT) is a technology for medical imaging whose
importance is increasing rapidly. There is a growing appreciation for the value of the …

The tau tangle ligand 18 F-AV-1451 (18 F-T807) binds to neuromelanin in the midbrain, and
may therefore be a measure of the pigmented dopaminergic neuronal count in the …

Appropriate application of spatially variant system models can correct for degraded
resolution response and mispositioning errors. This paper explores the detector blurring …

With the advantages of the increased sensitivity of fully 3-dimensional (3D) PET for whole-
body imaging come the challenges of more complicated quantitative corrections and, in …